ApoA1 Antibody (NT)

• Catalog number
  6712-100
• Price
  Please ask
• Size
  100 μl

• Antibody Target
  ApoA1
• Target Alternative Name
  APOA1; Apolipoprotein A-I; Apolipoprotein A1; Truncated apolipoprotein A-I; Apolipoprotein A-I(1-242)
• Antibody Type
  Polyclonal
• Species Reactivities
  Human
• Immunogen Sequence
  This APOA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 10-37 amino acids from the N-terminal region of human APOA1.
• Accession
  P02647
• Gene Id
  APOA1
• Appearance
  Colorless liquid
• Form
  Liquid
• Formulation
  100 µl of antibody in PBS with 0.09% (W/V) sodium azide
• Purification
  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
• Application
  Western blot, IHC
• Positive Control
  Western blot: HepG2 and 293 cell lysate, IHC: human placenta and hepatocarcinoma tissue
• Application And Usages
  Western blot: ~1:1000, IHC: ~1:10-1:50.
• Description
  APOA1 promotes cholesterol efflux from tissues to the liver for excretion. Apolipoprotein A-I is the major protein component of high density lipoprotein (HDL) in the plasma. Synthesized in the liver and small intestine, it consists of two identical chains of 77 amino acids; an 18-amino acid signal peptide is removed co-translationally and a 6-amino acid propeptide is cleaved post-translationally. Variation in the latter step, in addition to modifications leading to so-called isoforms, is responsible for some of the polymorphism observed. APOA1 is a cofactor for lecithin cholesterolacyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters. The APOA1, APOC3 and APOA4 genes are closely linked in both rat and human genomes. The A-I and A-IV genes are transcribed from the same strand, while the C-III gene is transcribed convergent in relation to A-I. Defects in the apolipoprotein A-1 gene are associated with HDL deficiency and Tangier disease.
• Storage Condition
  -20 °C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans.
• Handling
  The antibody solution should be gently mixed before use.
• Western Blot Verified
  Verified
• Immunocytochemistry Verified
  Verified
• Immunofluorescence Verified
  Not Verified
• Immunoprecipitation Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  ApoA1  
• Short name
  ApoA1 Antibody (NT)
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  apolipoprotein A-I (antibody to-) (NT)
• Alternative technique
  antibodies
• Alternative to gene target
  apolipoprotein A-I, APOA1 and IDBG-72644 and ENSG00000118137 and 335, lipoprotein particle binding, nuclei, Apoa1 and IDBG-161189 and ENSMUSG00000032083 and 11806, APOA1 and IDBG-630796 and ENSBTAG00000002258 and 281631

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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