Cathepsin L, human recombinant

• Catalog number
  1135-1000
• Price
  Please ask
• Size
  1 mg

• Synonyms
  Cathepsin
• Alternative_names
  Cathepsin L1, Major excreted protein, Cathepsin U, Cathepsin V
• Description
  Lysosomal cysteine protease involved in protein degradation, arthritis, apoptosis, and cancer
• Recombinant
  Yes
• Source
  E. coli
• Purity by SDS PAGE
  ≥90%
• Assay
  SDS-PAGE
• Activity Specifications test method
  > 10000 mU/mg (1 U = digestion of 1 µmole of Z-Phe-Arg-AFC substrate (K142-100) per minute at 37°C in 50 mM Sodium Acetate, 100 mM NaCl, pH 5.5).
• Biological activity
  > 10000 mU/mg (1 U = digestion of 1 µmole of Z-Phe-Arg-AFC substrate (K142-100) per minute at 37°C in 50 mM Sodium Acetate, 100 mM NaCl, pH 5.5).
• Results
  > 10000 mU/mg
• Unit Definition
  1 U = digestion of 1 µmole of Z-Phe-Arg-AFC substrate (K142-100) per minute at 37°C in 50 mM Sodium Acetate, 100 mM NaCl, pH 5.5
• Molecular Weight
  24.2 kDa (114-333 aa)
• Storage Temp
  -70°C
• Shipping
  Dry ice
• Shelf Life
  12 months
• Concentration
  0.5 mg/ml
• Appearance
  Liquid
• Physical form description
  0.5 mg/ml in 25 mM Sodium Acetate, 50 mM NaCl, pH 5.5 containing 50% glycerol
• Background Information
  Cathepsin L is a lysosomal protease that can be secreted from the cell and is implicated to play a role in protein degradation, arthritis, apoptosis, and cancer.
• Handling
  Centrifuge the vial prior to opening.
• Usage
  For Research Use Only! Not to be used in humans
• Datasheet
• Gene
  CTS protease activity also measured by zymograph electrophoresis of Cathepsins. This cathepsin is supplied in 1.
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  Cathepsin  
• Gene symbol
  CTSLP2, CTSL3P, CTSLP3
• Short name
  Cathepsin L, recombinant
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Species
  Human, Humans
• Alternative name
  Cathepsin L, H. sapiens Rec.
• Alternative technique
  rec

Gene info

• Identity
  HGNC:2540
• Gene
  CTSLP2
• Long gene name
  cathepsin L pseudogene 2
• Synonyms gene
  • CTSLL2
  • CTSL1P2
  • CTSLP5
  • CTSLL5
  • CTSL1P5
  • CTSLP7
  • CTSLL7
  • CTSL1P7
• Synonyms gene name
  • cathepsin L-like 2
  • cathepsin L1 pseudogene 2
  • cathepsin L pseudogene 5
  • cathepsin L-like 5
  • cathepsin L1 pseudogene 5
  • cathepsin L pseudogene 7
  • cathepsin L-like 7
  • cathepsin L1 pseudogene 7
• Synonyms
  • bA342C24.4
  • bA144G6.6
• GenBank acession
  • L25628
• Locus
  10q11.22
• Discovery year
  1993-12-06
• Entrez gene record
  1517
• Pubmed identfication
  • 7713509
• RefSeq identity
  • NR_033407
• VEGA ID
  OTTHUMG00000018112

Gene info

• Identity
  HGNC:33132
• Gene
  CTSL3P
• Long gene name
  cathepsin L family member 3, pseudogene
• Synonyms gene
  • CTSL3
• Synonyms gene name
  • cathepsin L family member 3
• Synonyms
  • HCTSL-s
• GenBank acession
  • AJ851862
• Locus
  9q21.33
• Discovery year
  2007-04-27
• Entrez gene record
  392360
• Pubmed identfication
  • 19663681
• RefSeq identity
  • NR_027917
• VEGA ID
  OTTHUMG00000020152

Gene info

• Identity
  HGNC:2541
• Gene
  CTSLP3
• Long gene name
  cathepsin L pseudogene 3
• Synonyms gene
  • CTSLL3
  • CTSL1P3
• Synonyms gene name
  • cathepsin L-like 3
  • cathepsin L1 pseudogene 3
• GenBank acession
  • L25629
• Locus
  10q11.22
• Discovery year
  1993-12-06
• Entrez gene record
  644021
• Pubmed identfication
  • 7713509
• RefSeq identity
  • NG_016830

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Product images

Similar products