EZH2 Inhibitor, EPZ005687[EZH2 Inhibitor, EPZ005687]

Products_type

Biochemical
Description

Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.

Identity

HGNC:3527
Gene

EZH2
Long gene name

enhancer of zeste 2 polycomb repressive complex 2 subunit
Synonyms gene name
- enhancer of zeste (Drosophila) homolog 2
- enhancer of zeste homolog 2 (Drosophila)
Synonyms
- EZH1
- ENX-1
- KMT6
- KMT6A
Locus

7q36.1
Discovery year

1995-12-21
Entrez gene record

2146
Pubmed identfication
- 8954776
- 17172412
RefSeq identity
- NM_004456
Classification
- SET domain containing
- Polycomb repressive complex 2
- Lysine methyltransferases
- Myb/SANT domain containing
VEGA ID

OTTHUMG00000158973
Locus Specific Databases
- LRG_531