Cathepsin Z, mouse recombinant

• Catalog number
  9233-25
• Price
  Please ask
• Size
  25 µg

• Synonyms
  CTSZ, AI787083, AU019819, CTSX, D2Wsu143e
• Alternative_names
  CTSZ, AI787083, AU019819, CTSX, D2Wsu143e
• Description
  A cysteine proteinases that represent a major component of the lysosomal proteolytic system
• Recombinant
  Yes
• Source
  Baculovirus, Insect cell
• Purity by SDS PAGE
  ≥90%
• Assay
  SDS-PAGE
• Purity
  ≥90%
• Molecular Weight
  This protein is fused with a 6× His tag at C-terminus and has a calculated MW of 32.8 kDa. The protein migrates as 28-40 kDa in SDS-PAGE under reducing conditions.
• Storage Temp
  -20°C
• Shipping
  Gel pack
• Shelf Life
  12 months
• Concentration
  0.5 mg/ml
• Appearance
  Liquid
• Physical form description
  Liquid
• Reconstitution Instructions
  In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol
• Background Information
  CTSZ, also known as cathepsin Z/X, is a relatively new cysteine protease of the papain family. Compared to other members of the papain family, CTSZ has a short proregion and unique insertions. Acting as a carboxypeptidase, CTSZ displays a unique specificity. Recombinant mouse CTSZ, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
• Amino acid sequence
  ARARLYFRSG QTCYHPIRGD QLALLGRRTY PRPHEYLSPA DLPKNWDWRN VNGVNYASVT RNQHIPQYCG SCWAHGSTSA MADRINIKRKGAWPSILLSV QNVIDCGNAG SCEGGNDLPV WEYAHKHGIP DETCNNYQAK DQDCDKFNQC GTCTEFKECH TIQNYTLWRV GDYGSLSGREKMMAEIYANG PISCGIMATE MMSNYTGGIY AEHQDQAVIN HIISVAGWGV SNDGIEYWIV RNSWGEPWGE KGWMRIVTST YKGGTGDSYNLAIESACTFG DPIVLEHHHH HH
• Handling
  Centrifuge the vial prior to opening.
• Usage
  For Research Use Only! Not to be used in humans
• Datasheet
• Gene
  CTS protease activity also measured by zymograph electrophoresis of Cathepsins. This cathepsin is supplied in 1.
• Test
  Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
• Latin name
  Mus musculus
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  Cathepsin  
• Gene symbol
  CTSZ
• Short name
  Cathepsin Z, mouse recombinant
• Technique
  Recombinant, Mouse, mouses, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Host
  mouse
• Species
  Mouse, Mouses
• Alternative name
  Cathepsin Z, mouse Rec.
• Alternative technique
  rec, murine

Gene info

• Identity
  HGNC:2547
• Gene
  CTSZ
• Long gene name
  cathepsin Z
• Synonyms
  • CTSX
• Synonyms name
  • cathepsin X
  • carboxypeptidase LB
  • cathepsin IV
  • cathepsin B2
  • cathepsin Y
  • cathepsin Z1
  • cysteine-type carboxypeptidase
  • lysosomal carboxypeptidase B
• GenBank acession
  • AF032906
• Locus
  20q13.32
• Discovery year
  1998-08-27
• Entrez gene record
  1522
• Pubmed identfication
  • 9642240
• RefSeq identity
  • NM_001336
• Classification
  • Cathepsins
• VEGA ID
  OTTHUMG00000032858

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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