anti-GLI2 Antibody

• Catalog number
  27-430
• Price
  Please ask
• Size
  100 ug

• Gene info
  GLI2 encodes a protein which belongs to the C2H2-type zinc finger protein subclass of the Gli family. Members of this subclass are characterized as transcription factors which bind DNA through zinc finger motifs. These motifs contain conserved H-C links. Gli family zinc finger proteins are mediators of Sonic hedgehog (Shh) signaling and they are implicated as potent oncogenes in the embryonal carcinoma cell. The protein encoded by this gene localizes to the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. It is also thought to play a role during embryogenesis. The encoded protein is associated with several phenotypes- Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, preaxial polydactyly type IV, postaxial polydactyly types A1 and B.
• Gene names
  GLI2, HPE9, THP1, THP2
• Antibodie s label
  unlabelled serum
• Purity
  Antibody is purified by protein A chromatography method.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Antigen
  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GLI2.
• Immuno application
  ELISA, Western Blot, immuno-histo-chemistry
• Antibody advice
  GLI2 antibody can be used for detection of GLI2 by ELISA at 1:312500. GLI2 antibody can be used for detection of GLI2 by western blot at 1.25 ug/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
• Suspention pH azide
  Antibody is lyophilized in PBS buffer with 2% sucrose. Add 100 μL of distilled water. Final antibody concentration is 1 mg/mL.
• Keep at
  For short periods of storage (days) store at 4 grades C. For longer periods of storage, store GLI2 antibody at -20 grades C. As with any antibody avoid repeat freeze-thaw cycles.
• Works with
  Human
• Omim nr
  13518231
• Ncbi nr
  NP_084655
• KDa
  133 kDa
• Vial with antibody
  Lyophilized
• Quantity per ml
  1 mg/ml
• NCBI GENE nr
  2736
• GENE symbol
  GLI2
• Antigene name
  GLI family zinc finger 2
• Source
  Homo sapiens
• Protein nr
  P10070
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  GLI2  
• Gene symbol
  GLI2
• Short name
  anti-GLI2 Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toGLI2 (antibody to-)
• Alternative technique
  antibodies
• Alternative to gene target
  GLI family zinc finger 2, HPE9 and PHS2 and THP1 and THP2, GLI2 and IDBG-68270 and ENSG00000074047 and 2736, metal ion binding, nuclei, Gli2 and IDBG-187317 and ENSMUSG00000048402 and 14633, GLI2 and IDBG-642543 and ENSBTAG00000011682 and

Gene info

• Identity
  HGNC:4318
• Gene
  GLI2
• Long gene name
  GLI family zinc finger 2
• Synonyms gene name
  • GLI-Kruppel family member GLI2
  • glioma-associated oncogene family zinc finger 2
• Synonyms
  • THP2
  • HPE9
  • THP1
• Synonyms name
  • tax-responsive element-2 holding protein
  • tax helper protein 1
  • tax helper protein 2
• Locus
  2q14.2
• Discovery year
  1989-05-25
• Entrez gene record
  2736
• Pubmed identfication
  • 2850480
  • 9557682
• RefSeq identity
  • NM_005270
• Classification
  • Zinc fingers C2H2-type
• VEGA ID
  OTTHUMG00000153741

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Similar products