STING AGONIST G10

• Catalog number
  B2047-25
• Price
  Please ask
• Size
  25 mg

• Alternative_name
  4-[(2-Chloro-6-fluorophenyl)methyl]-N-(2-furanylmethyl)-3,4-dihydro-3-oxo-2H-1,4-benzothiazine-6-carboxamide
• Description
  STING AGONIST G10 is an indirect activator of STING-dependent signaling. Stimulates IRF-3-induced transcription and induces IFNα and IFNγ gene expression in human fibroblasts.
• CAS Number
  702662-50-8
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₂₁H₁₆ClFN₂O₃S
• Molecular Weight
  430.88
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO (>20 mg/ml)
• Handling
  Protect from air and moisture
• Tag Line
  A STING ligand
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• PubChem CID
  5077622
• PubChem CID Link
• SMILES
  C1C(=O)N(C2=C(S1)C=CC(=C2)C(=O)NCC3=CC=CO3)CC4=C(C=CC=C4Cl)F
• InChi
  InChI=1S/C21H16ClFN2O3S/c22-16-4-1-5-17(23)15(16)11-25-18-9-13(6-7-19(18)29-12-20(25)26)21(27)24-10-14-3-2-8-28-14/h1-9H,10-12H2,(H,24,27)
• InChi Key
  NAGKYJATVFXZKN-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  STING   AGONIST   G10  
• Gene symbol
  ZBTB12, STING1, BUD31
• Short name
  STING AGONIST G10
• Alternative name
  STING AGONIST G10

Gene info

• Identity
  HGNC:19066
• Gene
  ZBTB12
• Long gene name
  zinc finger and BTB domain containing 12
• Synonyms gene
  • C6orf46
• Synonyms gene name
  • chromosome 6 open reading frame 46
• Synonyms
  • G10
  • NG35
  • D6S59E
• GenBank acession
  • BC043609
• Locus
  6p21.33
• Discovery year
  2002-08-13
• Entrez gene record
  221527
• Pubmed identfication
  • 9545376
• RefSeq identity
  • NM_181842
• Classification
  • BTB domain containing
  • Zinc fingers C2H2-type
• VEGA ID
  OTTHUMG00000031169

Gene info

• Identity
  HGNC:27962
• Gene
  STING1
• Long gene name
  stimulator of interferon response cGAMP interactor 1
• Synonyms gene
  • TMEM173
• Synonyms gene name
  • transmembrane protein 173
• Synonyms
  • FLJ38577
  • NET23
  • ERIS
  • MPYS
  • STING
  • MITA
• Synonyms name
  • stimulator of interferon genes
  • endoplasmic reticulum IFN stimulator
• Locus
  5q31.2
• Discovery year
  2006-08-24
• Entrez gene record
  340061
• Pubmed identfication
  • 21947006
• RefSeq identity
  • NM_198282
• VEGA ID
  OTTHUMG00000129239
• Locus Specific Databases
  • LRG_1308

Gene info

• Identity
  HGNC:29629
• Gene
  BUD31
• Long gene name
  BUD31 homolog
• Synonyms gene
  • G10
• Synonyms gene name
  • G10 maternal transcript homolog (Xenopus laevis)
  • BUD31 homolog (yeast)
  • BUD31 homolog (S. cerevisiae)
• Synonyms
  • YCR063W
  • EDG-2
  • EDG2
  • fSAP17
  • Cwc14
• Synonyms name
  • functional spliceosome-associated protein 17
• GenBank acession
  • BC022821
• Locus
  7q22.1
• Discovery year
  2006-03-10
• Entrez gene record
  8896
• Pubmed identfication
  • 7841202
• RefSeq identity
  • NM_003910
• Classification
  • Spliceosomal C complex
  • NTC associated proteins
  • Spliceosomal B complex
  • Spliceosomal Bact complex
  • Spliceosomal P complex
• VEGA ID
  OTTHUMG00000154602

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