NCGC00244536
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Catalog numberB1956-25
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PricePlease ask
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Size25 mg
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Alternative_name3-(8-hydroxyquinolin-6-yl)-N-(3-phenylpropyl)benzamide
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DescriptionNCGC00244536 is a potent KDM4A inhibitor (IC₅₀ = 10 nM). NCGC00244536 displays high selectivity for the fast-growing AR-negative PC3 cells (IC₅₀ = 40 nM) and over 100-fold selectivity against the immortalized prostate epithelial cell lines PrEC1 and PrEC4. Displays anticancer activity.
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CAS Number2003260-55-5
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Structure AvailableYes
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Salt FormNo
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Molecular FormulaC₂₅H₂₂N₂O₂
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Molecular Weight382.46
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Cell PermeableYes
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Purity≥98% by HPLC
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SolubilitiesDMSO
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HandlingProtect from air and light
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Tag LineA potent KDM4A inhibitor
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Storage Condition-20°C
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Shipping Conditiongel pack
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Shelf Life36 months
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PubChem CID127030711
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SMILESC1=CC=C(C=C1)CCCNC(=O)C2=CC=CC(=C2)C3=CC(=C4C(=C3)C=CC=N4)O
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InChiInChI=1S/C25H22N2O2/c28-23-17-22(16-20-12-6-13-26-24(20)23)19-10-4-11-21(15-19)25(29)27-14-5-9-18-7-2-1-3-8-18/h1-4,6-8,10-13,15-17,28H,5,9,14H2,(H,27,29)
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InChi KeyNYKBXXGHEMXSBB-UHFFFAOYSA-N
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MSDS AvailableYes
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Gene target
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Short nameNCGC00244536
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Alternative nameNCGC00244536
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