NCGC00244536

  • Catalog number
    B1956-25
  • Price
    Please ask
  • Size
    25 mg
  • Alternative_name
    3-(8-hydroxyquinolin-6-yl)-N-(3-phenylpropyl)benzamide
  • Description
    NCGC00244536 is a potent KDM4A inhibitor (IC₅₀ = 10 nM). NCGC00244536 displays high selectivity for the fast-growing AR-negative PC3 cells (IC₅₀ = 40 nM) and over 100-fold selectivity against the immortalized prostate epithelial cell lines PrEC1 and PrEC4. Displays anticancer activity.
  • CAS Number
    2003260-55-5
  • Structure Available
    Yes
  • Salt Form
    No
  • Molecular Formula
    C₂₅H₂₂N₂O₂
  • Molecular Weight
    382.46
  • Cell Permeable
    Yes
  • Purity
    ≥98% by HPLC
  • Solubilities
    DMSO
  • Handling
    Protect from air and light
  • Tag Line
    A potent KDM4A inhibitor
  • Storage Condition
    -20°C
  • Shipping Condition
    gel pack
  • Shelf Life
    36 months
  • PubChem CID
    127030711
  • SMILES
    C1=CC=C(C=C1)CCCNC(=O)C2=CC=CC(=C2)C3=CC(=C4C(=C3)C=CC=N4)O
  • InChi
    InChI=1S/C25H22N2O2/c28-23-17-22(16-20-12-6-13-26-24(20)23)19-10-4-11-21(15-19)25(29)27-14-5-9-18-7-2-1-3-8-18/h1-4,6-8,10-13,15-17,28H,5,9,14H2,(H,27,29)
  • InChi Key
    NYKBXXGHEMXSBB-UHFFFAOYSA-N
  • MSDS Available
    Yes
  • Gene target
  • Short name
    NCGC00244536
  • Alternative name
    NCGC00244536
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