TLR7 Antibody
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Catalog number3557-100
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PricePlease ask
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Size100 µl
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Antibody TargetTLR7
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Target Alternative NameTLR7 , Anti-TLR7 , PRO285 , UNQ248
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Antibody TypePolyclonal
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Species ReactivitiesHuman
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Immunogen SequenceSynthetic peptide surrounding amino acid 468 of human TLR7
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AccessionAAZ99026
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Gene Id74096726
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AppearanceColorless liquid
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FormLiquid
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Formulation100 µl affinity purified rabbit anti-TLR7 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.02% thimerosal.
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PurificationAffinity purified
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ApplicationWestern blot
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Application And UsagesWestern blotting (1:500-1000 dilution). However, the optimal conditions should be determined individually. Ramos cell lysate can be used as a positive control.
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DescriptionThe Toll-like receptor (TLR) family of proteins are characterized by a highly conserved Toll homology (TH) domain, which is essential for Toll-induced signal transduction. TLR1, as well as the other TLR family members, are type I transmembrane receptors that characteristically contain an extracellular domain consisting of several leucine-rich regions along with a single cytoplasmic Toll/IL-1R-like domain. TLR2 and TLR4 are activated in response to lipopolysacchride (LPS) stimulation, which results in the activation and translocation of NFkB and sμggests that these receptors are involved in mediating inflammatory responses. TLR6 and TLR7 induce NFkB signaling upon activation, sμggesting they play a role in immune reponse. Expression of TLR receptors is highest in peripheral blood leukocytes, macrophages, and monocytes.
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Storage Condition-20 °C
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Shipping Conditiongel pack
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Shelf Life12 months
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UsageFor Research Use Only! Not to be used in humans.
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HandlingThe antibody solution should be gently mixed before use.
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Western Blot VerifiedVerified
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Immunocytochemistry VerifiedNot Verified
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Immunofluorescence VerifiedNot Verified
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Immunoprecipitation VerifiedNot Verified
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ELISA VerifiedNot Verified
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ChIP VerifiedNot Verified
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Flow Cytometry VerifiedNot Verified
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PropertiesIf you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolTLR7
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Short nameTLR7 Antibody
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TechniqueAntibody, antibodies against human proteins, antibodies for
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IsotypeRabbit IgG
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Alternative nametoll-like receptor 7 (antibody to-)
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Alternative techniqueantibodies
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Alternative to gene targettoll-like receptor 7, TLR7 and IDBG-44230 and ENSG00000196664 and 51284, siRNA binding, Plasma membranes, Tlr7 and IDBG-185532 and ENSMUSG00000044583 and 170743, TLR7 and IDBG-639302 and ENSBTAG00000022161 and 493686
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Gene info
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Identity
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Gene
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Long gene nametoll like receptor 7
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Synonyms gene name
- toll-like receptor 7
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GenBank acession
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Locus
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Discovery year2001-04-27
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Toll like receptors
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data