Recombinant Mouse SLAM Family Member 8/SLAMF8 Protein(C-6His) 50µg
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Catalog number
PKSM041147-50µg
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Price
Please ask
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Size
50µg
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Activity
NA
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Synonym
SLAM family member 8; B-lymphocyte activator macrophage expressed; CD353; Slamf8; Blame
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Sequence
Val21-Asp231
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Fusion tag
C-6His
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Accession
Q9D3G2
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Expressed Host
Human Cells
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Shipping
The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.
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Purity
＞80% as determined by reducing SDS-PAGE.
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Stability and Storage
Lyophilized protein should be stored at < -20℃, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at < -20℃ for 3 months
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Mol Mass
24.2 kDa
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AP Mol Mass
32-38 kDa
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Formulation
Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
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Background
Mouse SLAM family member 8/SLAMF8 is a single-pass type I membrane protein. It contains one Ig-likeC2-type domain. SLAMF8 is expressed in lymphnode, spleen, thymus and bone marrow. The signaling lymphocyte activation molecule (SLAM) family includes homophilic and heterophilic receptors that modulate both adaptive and innate immune responses. These receptors share a common ectodomain organization: a membrane-proximal immunoglobulin constant domain and a membrane-distal immunoglobulin variable domain that is responsible for ligand recognition. SLAM family of receptors is expressed by a wide range of immune cells. Through their cytoplasmic domain, SLAM family receptors associate with SLAM-associated protein (SAP)-related molecules, a group of cytoplasmic adaptors composed almost exclusively of an SRC homology 2 domain. SLAM family receptors, inassociation with SAP family adaptors, have crucial roles during normal immune reactions in innate and adaptive immune cells. It may play a role in B-lineage commitment and/or modulation of signaling through the B-cell receptor.
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Test
Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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Latin name
Mus musculus
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Source
Recombinants or rec. proteins
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Group
recombinants
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Gene target
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Gene symbol
SLAMF1, SLAMF8
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Short name
Recombinant Mouse SLAM Family Member 8/SLAMF8 Protein(C-6His) 50µg
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Technique
Recombinant, Mouse, mouses, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
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Host
mouse
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Species
Mouse, Mouses
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Alternative name
Rec. Mouse SLAM family Member 8/SLAMF8 Protein(C-6His) 50µg
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Alternative technique
rec, murine
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Gene info
Gene info
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Identity
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Gene
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Long gene name
SLAM family member 8
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Synonyms
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GenBank acession
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Locus
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Discovery year
2003-10-29
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- CD molecules
- Immunoglobulin like domain containing
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VEGA ID
MeSH Data
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Name
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Concept
Scope note:
The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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