Tunicamycin

• Catalog number
  2802-25
• Price
  Please ask
• Size
  25 mg

• Alternative_name
  Tunicamycin from Streptomyces sp.
• Description
  From Streptomyces lysosuperificus. Provided as a mixture of tunicamycin A (C14), B (C15), C (C16) and D (C17) homologs in the fatty acid chain. Potent inhibitor of GlcNAc phosphotransferase which thereby inhibits glycoprotein biosynthesis. Causes endoplasmic reticulum stress-induced autophagy and unfolded protein response. Arrests cell cycle in late G1.
• CAS Number
  11089-65-9
• Structure Available
  Y
• Salt Form
  No
• Molecular Formula
  C₃₈H₆₂N₄O₆
• Molecular Weight
  830.93
• Cell Permeable
  Y
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO (~40 mg/ml) or EtOH (~5 mg/ml, warm)
• Handling
  Protect from air and light
• Tag Line
  A potent inhibitor of GlcNAc phosphotransferase
• Storage Condition
  -20°C
• Shipping Condition
  Gel Pack
• Shelf Life
  36 months
• MDL Number
  MFCD00065709
• PubChem CID
  71312646
• PubChem CID Link
• SMILES
  O[C@H]1[C@H](O)[C@@H](CO)O[C@H](O[C@H]2[C@H](NC(/C=C/CCCCCCCCCC(C)C)=O)[C@@H](O)[C@@H](O)[C@@H](C[C@@H](O)[C@@H]3[C@@H](O)[C@@H](O)[C@H](N4C=CC(NC4=O)=O)O3)O2)[C@@H]1N(C(C)=O)[H]
• InChi
  InChI=1S/C38H62N4O16/c1-19(2)13-11-9-7-5-4-6-8-10-12-14-24(46)40-27-31(51)28(48)22(55-37(27)58-36-26(39-20(3)44)30(50)29(49)23(18-43)56-36)17-21(45)34-32(52)33(53)35(57-34)42-16-15-25(47)41-38(42)54/h12,14-16,19,21-23,26-37,43,45,48-53H,4-11,13,17-18H2,1-3H3,(H,39,44)(H,40,46)(H,41,47,54)/b14-12+/t21-,22-,23-,26-,27-,28+,29-,30-,31-,32+,33-,34-,35-,36-,37+/m1/s1
• InChi Key
  MEYZYGMYMLNUHJ-DIRMKAHISA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  Tunicamycin  
• Short name
  Tunicamycin
• Alternative name
  Tunicamycin

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