GZD824

• Catalog number
  2795-5
• Price
  Please ask
• Size
  5 mg

• Alternative_name
  4-Methyl-N-[4-[(4-methyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-3-[2-(1H-pyrazolo[3,4-b]pyridin-5-yl)ethynyl]benzamide
• Description
  GZD824 is a novel orally bioavailable Bcr-Abl inhibitor for Bcr-Abl(WT) and Bcr-Abl(T315I) with IC₅₀ of 0.34 nM and 0.68 nM, respectively.
• CAS Number
  1257628-77-5
• Structure Available
  Y
• Salt Form
  No
• Molecular Formula
  C₂₉H₂₇F₃N₆O
• Molecular Weight
  532.56
• Cell Permeable
  Y
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO
• Handling
  Protect from air and light
• Tag Line
  An orally bioavailable Bcr-Abl inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  Gel Pack
• Shelf Life
  36 months
• PubChem CID
  51038269
• PubChem CID Link
• SMILES
  CC1=C(C=C(C=C1)C(=O)NC2=CC(=C(C=C2)CN3CCN(CC3)C)C(F)(F)F)C#CC4=CC5=C(NN=C5)N=C4
• InChi
  InChI=1S/C29H27F3N6O/c1-19-3-5-22(14-21(19)6-4-20-13-24-17-34-36-27(24)33-16-20)28(39)35-25-8-7-23(26(15-25)29(30,31)32)18-38-11-9-37(2)10-12-38/h3,5,7-8,13-17H,9-12,18H2,1-2H3,(H,35,39)(H,33,34,36)
• InChi Key
  TZKBVRDEOITLRB-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  GZD824  
• Short name
  GZD824
• Alternative name
  GZD824

Similar products