Fexaramine

• Catalog number
  B1156-5
• Price
  Please ask
• Size
  5 mg

• Alternative_name
  Methyl (E)-3-(3-(N-((4'-(dimethylamino)-[1,1'-biphenyl]-4-yl)methyl)cyclohexanecarboxamido)phenyl)acrylate
• Description
  Fexaramine is a potent, selective farnesoid X receptor (FXR) agonist (EC₅₀ = 25 nM). It displays no activity at hRXRα, hPPARα, hPPARγ, hPPARδ, mPXR, hPXR, hLXRα, hTRβ, hRARβ, mCAR, mERRγ and hVDR receptors. Fexaramine also demonstrates 100-fold increased affinity to FXR compared to endogenous bile acids .
• CAS Number
  574013-66-4
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₃₂H₃₆N₂O₃
• Molecular Weight
  498.65
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO (>40 mg/ml)
• Handling
  Protect from air and light
• Tag Line
  a potent, selective farnesoid X receptor (FXR) agonist
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• MDL Number
  MFCD09971007
• PubChem CID
  5326713
• PubChem CID Link
• SMILES
  CN(C)C1=CC=C(C=C1)C2=CC=C(C=C2)CN(C3=CC=CC(=C3)C=CC(=O)OC)C(=O)C4CCCCC4
• InChi
  InChI=1S/C32H36N2O3/c1-33(2)29-19-17-27(18-20-29)26-15-12-25(13-16-26)23-34(32(36)28-9-5-4-6-10-28)30-11-7-8-24(22-30)14-21-31(35)37-3/h7-8,11-22,28H,4-6,9-10,23H2,1-3H3/b21-14+
• InChi Key
  VLQTUNDJHLEFEQ-KGENOOAVSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  Fexaramine  
• Short name
  Fexaramine
• Alternative name
  Fexaramine

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