RARA polyclonal antibody

• Catalog number
  6826-50
• Price
  Please ask
• Size
  50 μl

• Antibody Target
  RARA
• Target Alternative Name
  Retinoic acid receptor alpha, Nuclear receptor subfamily 1 group B member 1, NR1B1
• Antibody Type
  Polyclonal
• Species Reactivities
  Human.
• Immunogen Sequence
  Human RARA (Retinoic Acid Receptor alpha) using two KLH-conjugated synthetic peptides containing sequences from the C-terminal region of the protein.
• Accession
  P10276
• Gene Id
  5914
• Appearance
  Colorless liquid
• Form
  Liquid
• Formulation
  In PBS with 0.05% (W/V) sodium azide.
• Purification
  Whole Anti-Sera
• Application
  Western blot, ELISA, ChIP.
• Positive Control
  Western blot: Human embryonic kidney cells, ELISA: peptides, ChIP: NB4 cells.
• Application And Usages
  ChIP: 4 µg/ChIP, WB: 1:750, ELISA: 1:50.
• Description
  RARA is a receptor for retinoic acid, a vitamin A metabolite, which directly regulates gene expression in target cells by binding to specific DNA response elements. In the absence of its ligand, this receptor represses transcription through the recruitment of specific corepressors and of HDAC’s, whereas binding of retinoic acid causes the recruitment of coactivators and HAT’s. Translocations involving the RARA gene, often leading to a RARA/PML fusion protein, are a major cause of acute promyelocytic leukemia.
• Storage Condition
  -20 °C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans.
• Handling
  The antibody solution should be gently mixed before use.
• Western Blot Verified
  Verified
• Immunocytochemistry Verified
  Not Verified
• Immunofluorescence Verified
  Not Verified
• Immunoprecipitation Verified
  Not Verified
• ELISA Verified
  Verified
• ChIP Verified
  Verified
• Dot Blot Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Group
  Polyclonals and antibodies
• About
  Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
• French translation
  anticorps

• Gene target
  RARA  
• Gene symbol
  RARA-AS1, RARA
• Short name
  RARA polyclonal antibody
• Technique
  Polyclonal, Antibody, antibodies against human proteins, antibodies for, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
• Isotype
  Rabbit IgG
• Alternative name
  retinoic acid receptor, alpha polyclonal (antibody to-)
• Alternative technique
  polyclonals, antibodies
• Alternative to gene target
  retinoic acid receptor, alpha, NR1B1 and RAR, RARA and IDBG-47411 and ENSG00000131759 and 5914, translation repressor activity, nuclei, Rara and IDBG-210842 and ENSMUSG00000037992 and 19401, RARA and IDBG-639652 and ENSBTAG00000012500 and 534280

Gene info

• Identity
  HGNC:49577
• Gene
  RARA-AS1
• Long gene name
  RARA antisense RNA 1
• GenBank acession
  • BC038432
• Locus
  17q21.2
• Discovery year
  2014-01-17
• Entrez gene record
  101929693
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000179631

Gene info

• Identity
  HGNC:9864
• Gene
  RARA
• Long gene name
  retinoic acid receptor alpha
• Synonyms gene name
  • retinoic acid receptor, alpha
• Synonyms
  • RAR
  • NR1B1
• GenBank acession
  • X06538
• Locus
  17q21.2
• Discovery year
  1988-06-09
• Entrez gene record
  5914
• Pubmed identfication
  • 2825036
  • 8244378
• Classification
  • Retinoic acid receptors
• VEGA ID
  OTTHUMG00000133328
• Locus Specific Databases
  • LRG_1070

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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