Fruquintinib

• Catalog number
  B1979-25
• Price
  Please ask
• Size
  25 mg

• Alternative_name
  (Z)-6-((6,7-dimethoxyquinazolin-4-yl)oxy)-N,2-dimethylbenzofuran-3-carbimidic acid; HMPL-013
• Description
  Fruquintinib (HMPL-013) is a potent and selective vascular endothelial growth factor receptors1/2/3 (VEGFR 1/2/3) inhibitor with IC₅₀s of 33, 0.35, and 35 nM, respectively. It only weakly inhibits RET, FGFR-1 and c-kit kinases. 
• CAS Number
  1194506-26-7
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₂₁H₁₉N₃O₅
• Molecular Weight
  393.39
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO (>6 mg/ml)
• Handling
  Protect from air and light
• Tag Line
  A potent VEGFR inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• PubChem CID
  44480399
• PubChem CID Link
• SMILES
  CC1=C(C2=C(O1)C=C(C=C2)OC3=NC=NC4=CC(=C(C=C43)OC)OC)C(=O)NC
• InChi
  InChI=1S/C21H19N3O5/c1-11-19(20(25)22-2)13-6-5-12(7-16(13)28-11)29-21-14-8-17(26-3)18(27-4)9-15(14)23-10-24-21/h5-10H,1-4H3,(H,22,25)
• InChi Key
  BALLNEJQLSTPIO-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  Fruquintinib  
• Short name
  Fruquintinib
• Alternative name
  Fruquintinib

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