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Alternative_name
(5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-penten-1-yl]cyclopentyl]-N-ethyl-5-heptenamide; AGN-192024; Lumigan; Prostamide;
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Description
Bimatoprost is a synthetic prostamide, structurally related to prostaglandin F2α. Bimatoprost is an antiglaucoma agent. Bimatoprost is converted by an amidase enzymatic activity in bovine and human cornea models to yield the corresponding free acid, 17-phenyl trinor PGF2α, a potent PGF2αR agonist. In human and animal models of glaucoma, FP receptor agonist activity corresponds very closely with intraocular hypotensive activity.
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CAS Number
155206-00-1
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Structure Available
Yes
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Salt Form
No
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Molecular Formula
C₂₅H₃₇NO₄
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Molecular Weight
415.57
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Cell Permeable
Yes
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Purity
≥98% by HPLC
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Solubilities
DMSO
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Handling
Protect from air and light
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Tag Line
Bimatoprost is an antiglaucoma agent
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Storage Condition
-20°C
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Shipping Condition
gel pack
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Shelf Life
36 months
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MDL Number
MFCD03411999
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PubChem CID
5311027
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SMILES
CCNC(=O)CCCC=CCC1C(CC(C1C=CC(CCC2=CC=CC=C2)O)O)O
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InChi
InChI=1S/C25H37NO4/c1-2-26-25(30)13-9-4-3-8-12-21-22(24(29)18-23(21)28)17-16-20(27)15-14-19-10-6-5-7-11-19/h3,5-8,10-11,16-17,20-24,27-29H,2,4,9,12-15,18H2,1H3,(H,26,30)/b8-3-,17-16+/t20-,21+,22+,23-,24+/m0/s1
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InChi Key
AQOKCDNYWBIDND-FTOWTWDKSA-N
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MSDS Available
Yes