Anti-CCL19/MIP-3 beta (Polyclonal), ALEXA Fluor 594

• Catalog number
  GENTObs-2454R-A594
• Price
  Please ask
• Size
  100 microliters

• Type
  Conjugated Primary Antibody
• Conjugated with
  ALEXA FLUOR® 594
• Host organism
  Rabbit (Oryctolagus cuniculus)
• Target Protein Peptide
  CCL19/MIP-3 beta
• Specificity
  This antibody reacts specifically with CCL19/MIP-3 beta
• Modification
  No modification has been applied to this antibody
• Modification site
  None
• Clonality
  Polyclonal Antibody
• Clone
  Polyclonal Antibodies
• Concentration
  1ug per 1ul
• Subcellular locations
  Secreted
• Antigen Source
  KLH conjugated synthetic peptide derived from mouse CCL19
• Gene ID
  24047
• Swiss Prot
  O70460
• Applications
  IF(IHC-P)
• Applications with corresponding dilutions
  IF(IHC-P)(1:50-200)
• Cross reactive species
  Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus)
• Cross Reactive Species details
  No significant cross reactivity has been observed for this antibody for the tested species. However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species.
• Background information
  Strongly chemotactic for naive (L-selectinhi) CD4 T-cells and for CD8 T-cells and weakly attractive for resting B-cells and memory (L-selectinlo) CD4 T-cells. May play a role in promoting encounters between recirculating T-cells and dendritic cells and in the migration of activated B-cells into the T-zone of secondary lymphoid tissues. Binds to chemokine receptor CCR7. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4.
• Purification method
  Purified by Protein A.
• Storage
  Water buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
• Excitation emission
  590nm/617nm
• Synonyms
  ELC; CKb11; MIP3B; Scya19; exodus-3; C-C motif chemokine 19; Epstein-Barr virus-induced molecule 1 ligand chemokine; EBI1 ligand chemokine; Small-inducible cytokine A19; Ccl19
• Also known as
  CCL19/MIP-3 beta Polyclonal Antibody
• Other name
  Anti-CCL19/MIP-3 beta Polyclonal
• Advisory
  Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody, thus reducing its reactivity, specificity and sensitivity. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
• Properties
  For facs or microscopy Alexa 1 conjugate.
• Conjugation
  Alexa Fluor, ALEXA FLUOR® 594
• Conjugated
  Alexa conjugate 1
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Group
  Polyclonals and antibodies
• About
  Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.

• Gene target
  CCL19/MIP-3   beta  
• Gene symbol
  CCL19, CCL26, CCL23, MIPEP, CCL15, TNPO1, MIP, MIR1302-3, MIR509-3
• Short name
  Anti-CCL19/MIP-3 beta
• Technique
  Polyclonal, anti-, anti, antibody to, antibodies, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 594
• Alternative name
  CCL19/MIP-3 beta Polyclonal Antibody, ALEXA FLUOR® 594 Conjugated
• Alternative technique
  polyclonals, antibodies
• Alternative to gene target
  chemokine (C-C motif) ligand 19, CKb11 and ELC and MIP-3b and MIP3B and SCYA19, CCL19 and IDBG-61011 and ENSG00000172724 and 6363, CCR chemokine receptor binding, Extracellular, CCL19 and IDBG-635974 and ENSBTAG00000012684 and 509167

Gene info

• Identity
  HGNC:10617
• Gene
  CCL19
• Long gene name
  C-C motif chemokine ligand 19
• Synonyms gene
  • SCYA19
• Synonyms gene name
  • small inducible cytokine subfamily A (Cys-Cys), member 19
  • chemokine (C-C motif) ligand 19
• Synonyms
  • ELC
  • MIP-3b
  • exodus-3
  • CKb11
• Synonyms name
  • CC chemokine ligand 19
  • macrophage inflammatory protein 3-beta
  • beta chemokine exodus-3
  • CK beta-11
  • EBI1-ligand chemokine
• GenBank acession
  • AB000887
• Locus
  9p13.3
• Discovery year
  1997-02-19
• Entrez gene record
  6363
• Pubmed identfication
  • 9153236
• RefSeq identity
  • NM_006274
• Classification
  • Chemokine ligands
• VEGA ID
  OTTHUMG00000019833

Gene info

• Identity
  HGNC:10625
• Gene
  CCL26
• Long gene name
  C-C motif chemokine ligand 26
• Synonyms gene
  • SCYA26
• Synonyms gene name
  • small inducible cytokine subfamily A (Cys-Cys), member 26
  • chemokine (C-C motif) ligand 26
• Synonyms
  • MIP-4alpha
  • eotaxin-3
  • IMAC
  • MIP-4a
  • TSC-1
• Synonyms name
  • macrophage inflammatory protein 4-alpha
  • small inducible cytokine A26
  • CC chemokine IMAC
  • chemokine N1
  • thymic stroma chemokine-1
  • eotaxin-3
• GenBank acession
  • AF124601
• Locus
  7q11.23
• Discovery year
  1999-06-09
• Entrez gene record
  10344
• Pubmed identfication
  • 10373330
• RefSeq identity
  • NM_006072
• Classification
  • Chemokine ligands
• VEGA ID
  OTTHUMG00000130403

Gene info

• Identity
  HGNC:10622
• Gene
  CCL23
• Long gene name
  C-C motif chemokine ligand 23
• Synonyms gene
  • SCYA23
• Synonyms gene name
  • small inducible cytokine subfamily A (Cys-Cys), member 23
  • chemokine (C-C motif) ligand 23
• Synonyms
  • Ckb-8
  • MPIF-1
  • MIP-3
  • CKb8
• GenBank acession
  • U58913
• Locus
  17q12
• Discovery year
  1997-11-14
• Entrez gene record
  6368
• Pubmed identfication
  • 9104803
  • 10409433
• RefSeq identity
  • NM_005064
  • NM_145898
• Classification
  • Chemokine ligands
• VEGA ID
  OTTHUMG00000188409

Gene info

• Identity
  HGNC:7104
• Gene
  MIPEP
• Long gene name
  mitochondrial intermediate peptidase
• Synonyms
  • MIP
• Locus
  13q12.12
• Discovery year
  1996-10-30
• Entrez gene record
  4285
• Pubmed identfication
  • 9073519
  • 33669127
• Classification
  • M3 metallopeptidase family
• VEGA ID
  OTTHUMG00000016573

Gene info

• Identity
  HGNC:10613
• Gene
  CCL15
• Long gene name
  C-C motif chemokine ligand 15
• Synonyms gene
  • SCYA15
• Synonyms gene name
  • small inducible cytokine subfamily A (Cys-Cys), member 15
  • chemokine (C-C motif) ligand 15
• Synonyms
  • HCC-2
  • NCC-3
  • SCYL3
  • MIP-5
  • Lkn-1
  • MIP-1d
  • HMRP-2B
• Synonyms name
  • leukotactin 1
  • CC chemokine 3
  • macrophage inflammatory protein 5
  • chemokine CC-2
  • MIP-1 delta
• GenBank acession
  • AF031587
• Locus
  17q12
• Discovery year
  1997-02-11
• Entrez gene record
  6359
• Pubmed identfication
  • 8661057
• RefSeq identity
  • NM_004167
• Classification
  • Chemokine ligands
• VEGA ID
  OTTHUMG00000188406

Gene info

• Identity
  HGNC:6401
• Gene
  TNPO1
• Long gene name
  transportin 1
• Synonyms gene
  • KPNB2
• Synonyms gene name
  • karyopherin (importin) beta 2
• Synonyms
  • MIP
  • TRN
  • IPO2
  • MIP1
• Synonyms name
  • importin 2
• GenBank acession
  • U70322
• Locus
  5q13.2
• Discovery year
  1997-04-21
• Entrez gene record
  3842
• Pubmed identfication
  • 8808633
  • 9144189
• RefSeq identity
  • NM_002270
• Classification
  • Importins
  • Armadillo like helical domain containing
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000100967

Gene info

• Identity
  HGNC:7103
• Gene
  MIP
• Long gene name
  major intrinsic protein of lens fiber
• Synonyms
  • MP26
  • LIM1
  • AQP0
• Synonyms name
  • aquaporin 0
• Locus
  12q13.3
• Discovery year
  2001-06-22
• Entrez gene record
  4284
• Pubmed identfication
  • 1840563
  • 7536742
• RefSeq identity
  • NM_012064
• Classification
  • Aquaporins
• VEGA ID
  OTTHUMG00000170571
• Locus Specific Databases
  • LRG_1291

Gene info

• Identity
  HGNC:35295
• Gene
  MIR1302-3
• Long gene name
  microRNA 1302-3
• Synonyms gene
  • MIRN1302-3
• Synonyms
  • hsa-mir-1302-3
• Locus
  2q14.1
• Discovery year
  2008-11-03
• Entrez gene record
  100302128
• RefSeq identity
  • NR_031632
• Classification
  • MicroRNA MIR1302 family

Gene info

• Identity
  HGNC:33675
• Gene
  MIR509-3
• Long gene name
  microRNA 509-3
• Synonyms gene
  • MIRN509-3
• Synonyms
  • hsa-mir-509-3
• Locus
  Xq27.3
• Discovery year
  2007-10-24
• Entrez gene record
  100126337
• RefSeq identity
  • NR_030629
• Classification
  • MicroRNA MIR506 family

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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