Mouse Monoclonal [clone MEM-E/02] (IgG1) to Human HLA-E[HLA-E]

Products_type

Antibody
Products_gene_name

[HLA-E]
Reactivity

Human, Primate
Properties

Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
About

Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
Test

Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
Latin name

Mus musculus

Gene target

Monoclonal MEM-E/02] IgG1 HLA-E[HLA-E]
Gene symbol

HLA-E, SMC2, SNAR-E, IPCEF1, SNRPE, KLRC3, TLE4, IGHV1-69, GUCY2EP
Short name

Mouse Monoclonal [clone MEM-E/02] (IgG1) HLA-E[HLA-E]
Technique

Mouse monoclonal, Mouse, Monoclonals or monoclonal antibodies, mouses, mouse monoclonals
Host

Mouse, Murine monoclonal antibodies or Mabs are often conjugated and the isotype is IgG.
Isotype

IgG1
Species

Human, Humans, Mouses
Alternative name

Mouse monoclonal [clonality MEM-E/02] (IgG1) to H. sapiens major histocompatibility complex, class I, E[major histocompatibility complex, class I, E]
Alternative technique

murine
Alternative to gene target

major histocompatibility complex, class I, E, EA1.2 and EA2.1 and HLA-6.2 and MHC and QA1, HLA-E and IDBG-125081 and ENSG00000204592 and 3133, peptide antigen binding, Plasma membranes
Clone name

MEM-E

Identity

HGNC:14011
Gene

SMC2
Long gene name

structural maintenance of chromosomes 2
Synonyms gene
- SMC2L1
Synonyms gene name
- SMC2 (structural maintenance of chromosomes 2, yeast)-like 1
- SMC2 structural maintenance of chromosomes 2-like 1 (yeast)
Synonyms
- hCAP-E
- CAP-E
GenBank acession
- AF092563
Locus

9q31.1
Discovery year

2001-02-22
Entrez gene record

10592
Pubmed identfication
- 9789013
Classification
- Condensin I subunits
- Condensin II subunits
- Structural maintenance of chromosomes proteins
VEGA ID

OTTHUMG00000020401

Identity

HGNC:6376
Gene

KLRC3
Long gene name

killer cell lectin like receptor C3
Synonyms gene name
- killer cell lectin-like receptor subfamily C, member 3
Synonyms
- NKG2-E
GenBank acession
- L14542
Locus

12p13.2
Discovery year

1998-01-16
Entrez gene record

3823
Pubmed identfication
- 9598306
RefSeq identity
- NM_002261
Classification
- C-type lectin domain containing
- Killer cell lectin like receptors
VEGA ID

OTTHUMG00000167149

Identity

HGNC:11840
Gene

TLE4
Long gene name

TLE family member 4, transcriptional corepressor
Synonyms gene name
- transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
- transducin like enhancer of split 4
Synonyms
- E(spl)
- ESG
- GRG4
GenBank acession
- M99439
Locus

9q21.31
Discovery year

1993-12-20
Entrez gene record

7091
Pubmed identfication
- 8365415
RefSeq identity
- NM_001282748
Classification
- WD repeat domain containing
- TLE family
- Wnt enhanceosome complex
VEGA ID

OTTHUMG00000020072

Name

Blood Grouping and Crossmatching
Concept

Scope note: Testing erythrocytes to determine presence or absence of blood-group antigens, testing of serum to determine the presence or absence of antibodies to these antigens, and selecting biocompatible blood by crossmatching samples from the donor against samples from the recipient. Crossmatching is performed prior to transfusion.
Tree numbers
- E01.370.225.625.120
- E01.370.225.812.385.120
- E05.200.625.120
- E05.200.812.385.120
- E05.478.594.385.120
Qualifiers

ethics, mortality, psychology, trends, veterinary, history, classification, economics, instrumentation, methods, nursing, standards, adverse effects, statistics & numerical data