APG7 Antibody, ALEXA FLUOR 594

• Catalog number
  bs-2432R-A594
• Price
  Please ask
• Size
  100ul

• Long name
  APG7 Polyclonal Antibody, ALEXA FLUOR 594 Conjugated
• Also known as
  Anti-APG7 PAb ALEXA FLUOR 594
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 594
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  APG7
• Specificity
  This is a highly specific antibody against APG7.
• Modification
  Unmodified
• Modification Site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  1-50/70
• Subcellular location
  Cytoplasm
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ATG7
• Gene ID Number
  10533
• Swiss Prot
  O95352
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Modulates p53/TP53 activity to regulate cell cycle and survival during metabolic stress. Plays also a key role in the maintenance of axonal homeostasis, the prevention of axonal degeneration, the maintenance of hematopoietic stem cells, the formation of Paneth cell granules, as well as in adipose differentiation.
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  590nm/617nm
• Synonyms
  GSA7; APG7L; APG7-LIKE; Ubiquitin-like modifier-activating enzyme ATG7; ATG12-activating enzyme E1 ATG7; Autophagy-related protein 7; hAGP7; Ubiquitin-activating enzyme E1-like protein; ATG7
• Properties
  For facs or microscopy Alexa 1 conjugate. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor, ALEXA FLUOR® 594
• Conjugated
  Alexa conjugate 1
• French translation
  anticorps

• Gene target
  APG7  
• Gene symbol
  ATG7
• Short name
  Anti-APG7
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 594
• Alternative name
  APG7 Polyclonal Antibody, ALEXA FLUOR 594
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:16935
• Gene
  ATG7
• Long gene name
  autophagy related 7
• Synonyms gene
  • APG7L
• Synonyms gene name
  • APG7 autophagy 7-like (S. cerevisiae)
  • ATG7 autophagy related 7 homolog (S. cerevisiae)
• Synonyms
  • GSA7
  • DKFZp434N0735
• Synonyms name
  • ubiquitin-activating enzyme E1-like protein
• GenBank acession
  • AF094516
• Locus
  3p25.3
• Discovery year
  2003-11-20
• Entrez gene record
  10533
• Pubmed identfication
  • 10233149
• RefSeq identity
  • NM_006395
• Classification
  • Ubiquitin like modifier activating enzymes
  • Autophagy related
• VEGA ID
  OTTHUMG00000129740

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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