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Human CellExp ErbB3 HER3 human recombinant

Human CellExp ErbB3 HER3 human recombinant is available 2 times from Biovision labs

7400-50 | Human CellExp ErbB3/HER3, human recombinant size: 50 μg | 847.14 USD

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7400-10 | Human CellExp ErbB3/HER3, human recombinant size: 10 μg | 375.24 USD

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Synonyms ERBB3, ErbB-3, HER3, HER-3, LCCS2, MDA-BF-1, MGC88033, c-erbB-3, c-erbB3, erbB3-S, p180-ErbB3, p45-sErbB3, p85-sErbB3, Receptor tyrosine-protein kinase erbB-3
Alternates names ERBB3, ErbB-3, HER3, HER-3, LCCS2, MDA-BF-1, MGC88033, c-erbB-3, c-erbB3, erbB3-S, p180-ErbB3, p45-sErbB3, p85-sErbB3, Receptor tyrosine-protein kinase erbB-3
Taglines Involved in pathways leading to cell proliferation or differentiation.
Biomolecule/Target ErbB3
NCBI Gene ID #. 2065
NCBI Gene Symbol ErbB3
Gene Source Human
Accession # P21860
Recombinant Yes
Source HEK293 cells
Purity N/A
Activity (Specifications/test method) N/A
Biological activity Measured by its ability to inhibit the biological activity of Neuregulin1-β1 on MCF-7 human breast cancer cells, in the presence of 10 ng/ml recombinant Human NRG1-β1/HRG1-β1 Extracellular Domain. The ED50 for this effect is typically 0.5-3.0 μg/ml
Results Measured by its ability to inhibit the biological activity of Neuregulin1-β1 on MCF-7 human breast cancer cells, in the presence of 10 ng/ml recombinant Human NRG1-β1/HRG1-β1 Extracellular Domain. The ED50 for this effect is typically 0.5-3.0 μg/ml
Molecular Weight This protein is fused with a C-terminal 6×his tag and has a calculated MW of 71.5 kDa after removal of signal peptide. The predicted N-terminal is Ser 20. Protein migrates as 100-110 kDa in reduced SDS-PAGE resulting from glycosylation.
Storage Temp. -20°C
Shipping Gel Pack
Shelf Life 1 year
Concentration N/A
Appearance Lyophilized
Physical form description Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Generally 5-8% Mannitol or trehalose is added as a protectant before lyophilization.
Reconstitution Instructions Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 µg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 month. For extended storage, it is recommended to store at -20°C.
Handling Centrifuge the vial prior to opening.
Usage For Research Use Only! Not to be used in humans
Properties Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Additional source Recombinants or rec. proteins
Group recombinants
Gene targetCellExp ErbB3/HER3
Short name CellExp ErbB3/HER3, recombinant
Technique Recombinant
Species Human
Alternative name H. sapiens CellExp v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)/HER3, H. sapiens recombinant
Alternative technique rec
Alternative to gene target v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian), c-erbB-3 and c-erbB3 and ErbB-3 and erbB3-S and HER3 and LCCS2 and MDA-BF-1 and p180-ErbB3 and p45-sErbB3 and p85-sErbB3, ERBB3 and IDBG-39824 and ENSG00000065361 and 2065, transferase activity, Extracellular, Erbb3 and IDBG-197943 and ENSMUSG00000018166 and 13867, ERBB3 and IDBG-636302 and ENSBTAG00000010444 and 785655
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