anti- DR1 antibody

• Catalog number
  FNab02527
• Price
  Please ask
• Size
  2X100μg

• Form
  liquid
• Purification
  Immunogen affinity purified
• Purity
  ≥95% as determined by SDS-PAGE
• Storage
  PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
• Background
  This gene encodes a TBP- (TATA box-binding protein) associated phosphoprotein that represses both basal and activated levels of transcription. The encoded protein is phosphorylated in vivo and this phosphorylation affects its interaction with TBP. This protein contains a histone fold motif at the amino terminus, a TBP-binding domain, and a glutamine- and alanine-rich region. The binding of DR1 repressor complexes to TBP-promoter complexes may establish a mechanism in which an altered DNA conformation, together with the formation of higher order complexes, inhibits the assembly of the preinitiation complex and controls the rate of RNA polymerase II transcription.
• Immunogen
  down-regulator of transcription 1, TBP-binding (negative cofactor 2)
• Calculated MW
  19 kDa
• Uniprot ID
  Q01658
• Specificity
  Human, Mouse, Rat
• Tested Application
  ELISA, WB, IHC
• Recommended dilution
  WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200
• Image1
  Immunohistochemistry of paraffin-embedded human breast cancer using FNab02527(DR1 antibody) at dilution of 1:10
• Image4
  mouse testis tissue were subjected to SDS PAGE followed by western blot with FNab02527(DR1 antibody) at dilution of 1:1000
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
• Properties
  If you buy Antibodies supplied by FineTest they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  DR1  
• Gene symbol
  DR1, CHRFAM7A
• Short name
  anti- DR1 antibody
• Technique
  Antibody, anti, antibody to, antibodies against human proteins, antibodies for
• Host
  Rabbit
• Isotype
  IgG
• Alternative name
  antibody to- DR1 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:3017
• Gene
  DR1
• Long gene name
  down-regulator of transcription 1
• Synonyms gene name
  • down-regulator of transcription 1, TBP-binding (negative cofactor 2)
• Synonyms
  • NC2-BETA
  • NC2B
  • NCB2
• Synonyms name
  • negative cofactor 2
  • negative cofactor 2 beta
• GenBank acession
  • M97388
• Locus
  1p22.1
• Discovery year
  1996-07-11
• Entrez gene record
  1810
• Pubmed identfication
  • 1339312
  • 9040789
• RefSeq identity
  • NM_001938
• Classification
  • ATAC complex
• VEGA ID
  OTTHUMG00000010862

Gene info

• Identity
  HGNC:15781
• Gene
  CHRFAM7A
• Long gene name
  CHRNA7 (exons 5-10) and FAM7A (exons A-E) fusion
• Synonyms gene name
  • CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion
• Synonyms
  • D-10
  • CHRNA7-DR1
• GenBank acession
  • AF029838
• Locus
  15q13.2
• Discovery year
  2001-06-29
• Entrez gene record
  89832
• Pubmed identfication
  • 11829490
• RefSeq identity
  • NM_148911
• VEGA ID
  OTTHUMG00000175645

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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