Kobe0065
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Catalog numberB1714-25
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PricePlease ask
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Size25 mg
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Alternative_nameKobe0065; Kobe 0065; Kobe-0065; N-(3-chloro-4-methylphenyl)-2-(2,6-dinitro-4-(trifluoromethyl)phenyl)hydrazinecarbothioamide; 1-(3-chloro-4-methylphenyl)-3-[2,6-dinitro-4-(trifluoromethyl)anilino]thiourea
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DescriptionKobe0065 is a small-molecule inhibitor of Ras with Ki value of 46 μM for the binding of H-Ras.GTP to c-Raf-1
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CAS Number436133-68-5
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Structure AvailableYes
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Salt FormNo
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Molecular FormulaC₁₅H₁₁ClF₃N₅O₄S
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Molecular Weight449.79
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Cell PermeableYes
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Purity>98%
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SolubilitiesDMSO
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HandlingProtect from air and light
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Tag LineA small-molecule Ras inhibitor
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Storage Condition-20°C
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Shipping Conditiongel pack
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Shelf Life36 months
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MDL NumberMFCD04109603
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PubChem CID3827663
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SMILESCC1=C(C=C(C=C1)NC(=S)NNC2=C(C=C(C=C2[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-])Cl
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InChiInChI=1S/C15H11ClF3N5O4S/c1-7-2-3-9(6-10(7)16)20-14(29)22-21-13-11(23(25)26)4-8(15(17,18)19)5-12(13)24(27)28/h2-6,21H,1H3,(H2,20,22,29)
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InChi KeyKSJVAYBCXSURMQ-UHFFFAOYSA-N
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MSDS AvailableYes
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Gene target
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Short nameKobe0065
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Alternative nameKobe0065
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