Recombinant Human Plasma Kallikrein/KLKB1 Protein(C-6His) 50µg

• Catalog number
  PKSH032901-50µg
• Price
  Please ask
• Size
  50µg

• Synonym
  Plasma kallikrein;Fletcher factor;Kininogenin;Plasma prekallikrein;KLKB1;KLK3
• Activity
  NA
• Sequence
  Gly20-Ala638
• Fusion tag
  C-6His
• Accession
  P03952
• Expressed Host
  Human cells
• Shipping
  The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.
• Purity
  ＞95% as determined by reducing SDS-PAGE.
• Endotoxin
  ＜1.0 EU per µg as determined by LAL test.
• Stability and Storage
  Store at < -20℃, stable for 6 monthshs after receipt.Please minimize freeze-thaw cycles
• Mol Mass
  70.2 kDa
• AP Mol Mass
  75-87 kDa
• Formulation
  Supplied as a 0.2 μm filtered solution of 20mM TrisHCl,150mM NaCl,10% Glycerol,pH8.0.
• Reconstitution
  Please refer to it for detailed information.
• Background
  KLKB1 is a 638 amino acids protein that belongs to the peptidase S1 family and plasma kallikrein subfamily. It contains a peptidase S1 domain and four apple domains. The enzyme cleaves Lys-Arg and Arg-Ser bonds. It activates, in a reciprocal reaction, factor XII after its binding to a negatively charged surface. It also releases bradykinin from HMW kininogen and may also play a role in the renin-angiotensin system by converting prorenin into renin. It participates in the surface-dependent activation of blood coagulation, fibrinolysis, kinin generation and inflammation.Plasma prekallikrein deficiency causes a prolonged activated partial thromboplastin time in patients.
• Product URL
• PDF URL
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  Plasma   Kallikrein/KLKB1   Protein   C-6His   50µg  
• Gene symbol
  KLKB1
• Short name
  Recombinant Plasma Kallikrein/KLKB1 Protein(C-6His) 50µg
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Species
  Human, Humans
• Alternative name
  Rec. H. sapiens Plasma Kallikrein/KLKB1 Protein(C-6His) 50µg
• Alternative technique
  rec

Gene info

• Identity
  HGNC:6371
• Gene
  KLKB1
• Long gene name
  kallikrein B1
• Synonyms gene
  • KLK3
• Synonyms gene name
  • kallikrein B, plasma (Fletcher factor) 1
• Synonyms name
  • Fletcher factor
• GenBank acession
  • M13143
• Locus
  4q35.2
• Discovery year
  1999-04-23
• Entrez gene record
  3818
• Pubmed identfication
  • 9535413
  • 3521732
• RefSeq identity
  • NM_000892
• Classification
  • Kallikreins
• VEGA ID
  OTTHUMG00000150347
• Locus Specific Databases
  • LRG_565

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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