RAT ANTI MOUSE CD104 Antibody
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Catalog number
GEN216005
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Price
Please ask
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Size
0.025 miligrams
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Also known as
CD104
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Other names
Integrin beta-4; Integrin beta-4; integrin beta-4; integrin beta 4; N/A
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Category
Antibodies
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Subcategory
Mnoclonal antibodies
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Gene name
CD104
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Gene name synonims
N/A
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Other gene names
Itgb4; Itgb4; CD104; AA407042; C230078O20; N/A
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Clonality
Monoclonal
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Immunoglobulin isotype
IgG2a
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Clone
346-11A
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Host organism
Rat (Rattus norvegicus)
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Species reactivity
Mouse (Mus musculus); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
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Specificity and cross reactivity
CD104 Recognises mouse integrin beta 4 (CD104), a 200kD glycoprotein that can associate with integrin alpha 6 (CD49f) to form a heterodimer on the cell surface. _x000D__x000D_Expression of CD104 is localised to the basal region of a wide variety of epithelial cells. In mice, CD104 is also expressed on peripheral neurones, carcinoma cell lines and a subset of endothelial cells. _x000D__x000D_The alpha 6 beta 4 (CD49f/CD104) integrin has been identified as a component of hemidesmosomes in stratified squamous epithelium where it plays an important role in the adhesion of epithelia to basement membrane. _x000D__x000D_Studies suggest that the CD49f/CD104 integrin is involved in cell matrix adhesion but expression of the CD49f/CD104 integrin in endothelial cells is thought to have a different function.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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Purification method
N/A
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Form Appearance
Purified (Purified IgG - liquid)
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Concentration
IgG concentration 1.0 mg/ml
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Storage and shipping
Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term.Storage in frost-free freezers is not recommended. the antibody should be stored undiluted. Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided. If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use. Shelf Life: 18 months from date of dispatch.
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Tested applications
Western Blot (WB), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistology - Frozen (IHC)
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Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. This is against a protein of mus musculus directed antibody.
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Properties
If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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Test
Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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Latin name
Mus musculus, Rattus norvegicus
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About
Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.
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French translation
anticorps
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Gene target
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Gene symbol
ITGB4
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Short name
ANTI MOUSE CD104 Antibody
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Technique
anti mouse, Antibody, Mouse, anti, antibody to, anti mouse antibodies, antibodies against human proteins, antibodies for, mouses
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Host
Rat
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Species
Mouse, Mouses, Rats
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Alternative name
Anti-RAT ANTI MOUSE CD104
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Alternative technique
antibodies, murine
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Gene info
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Identity
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Gene
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Long gene name
integrin subunit beta 4
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Synonyms gene name
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Synonyms
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Locus
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Discovery year
1991-08-06
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Entrez gene record
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Pubmed identfication
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Classification
- Integrin beta subunits
- Fibronectin type III domain containing
- CD molecules
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VEGA ID
MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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