Neurotrophic Tyrosine Kinase Receptor Type 1 (NTRK1) Monoclonal Antibody (Human), FITC

• Catalog number
  MAC182Hu21-100ul-FITC
• Price
  Please ask
• Size
  100ul

• Description
  A Mouse monoclonal antibody against Human Neurotrophic Tyrosine Kinase Receptor Type 1 (NTRK1). This antibody is labeled with FITC.
• Specifications
  Host: Mouse; Species Reactivity: Human; Clonality: monoclonal; Tested applications: WB; IHC; ICC; IP.; Concentration: 1mg/mL; Isotype: IgG1 Kappa; Conjugation: FITC
• Additional_information
  Sequence of the immunogen: Inquire for antigen sequence.; Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
• Storage_and_shipping
  Upon receipt, store at -20°C or -80°C. Prepare working aliqotes prior to storage to avoid repeated freeze-thaw cycles.
• Notes
  Research Use Only.
• Properties
  If you buy Antibodies supplied by Cloud Clone Corp they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. This Cloud Clone Corp Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS. When excited at 488 nanometers, FITC has a green emission that's usually collected at 530 nanometers, the FL1 detector of a FACSCalibur or FACScan. FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light. For fluorescent microscopy applications, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept. Cloud Clone Corp FITC is highly sensitive to pH extremes. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Conjugation
  Anti-FITC Antibody
• About
  Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
• Additional description
  The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
• French translation
  anticorps

• Gene target
  Neurotrophic   Tyrosine   Kinase   Receptor   NTRK1   Monoclonal  
• Gene symbol
  NTRK1
• Short name
  Neurotrophic Tyrosine Kinase Receptor 1 (NTRK1) Monoclonal Antibody ( ), FITC
• Technique
  Antibody, FITC, antibodies against human proteins, antibodies for, Fluorescein, Monoclonals or monoclonal antibodies
• Label
  FITC
• Species
  Human, Humans
• Alternative name
  Neurotrophic Tyrosine phosphorylation catalyst Receptor classification 1 (neurotrophic tyrosine kinase, receptor, classification 1) monoclonal (antibody to-) (H. sapiens), fluorecein
• Alternative technique
  antibodies, fluorescine
• Alternative to gene target
  neurotrophic tyrosine kinase, receptor, type 1, MTC and p140-TrkA and TRK and Trk-A and TRK1 and TRKA, NTRK1 and IDBG-103632 and ENSG00000198400 and 4914, transferase activity, Cell surfaces, Ntrk1 and IDBG-158646 and ENSMUSG00000028072 and 18211, BT.22873 and IDBG-631386 and ENSBTAG00000003060 and 353111

Gene info

• Identity
  HGNC:8031
• Gene
  NTRK1
• Long gene name
  neurotrophic receptor tyrosine kinase 1
• Synonyms gene name
  • neurotrophic tyrosine kinase, receptor, type 1
• Synonyms
  • TRK
  • TRKA
  • MTC
• Synonyms name
  • high affinity nerve growth factor receptor
• GenBank acession
  • Y09028
• Locus
  1q23.1
• Discovery year
  1991-07-18
• Entrez gene record
  4914
• Pubmed identfication
  • 2869410
• RefSeq identity
  • NM_002529
• Classification
  • Immunoglobulin like domain containing
  • Receptor tyrosine kinases
• VEGA ID
  OTTHUMG00000041304
• Locus Specific Databases
  • Inherited Peripheral Neuropathies Mutation Database
  • LRG_261

MeSH Data

• Name
  Fluorescent Antibody Technique
• Concept
  Scope note: Test for tissue antigen using either a direct method, by conjugation of antibody with fluorescent dye (FLUORESCENT ANTIBODY TECHNIQUE, DIRECT) or an indirect method, by formation of antigen-antibody complex which is then labeled with fluorescein-conjugated anti-immunoglobulin antibody (FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT). The tissue is then examined by fluorescence microscopy.
• Tree numbers
  • E01.370.225.500.607.512.240
  • E01.370.225.750.551.512.240
  • E05.200.500.607.512.240
  • E05.200.750.551.512.240
  • E05.478.583.375
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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