Tripolin A

• Catalog number
  2307-1
• Price
  Please ask
• Size
  1 mg

• Alternative_name
  (3E)-3-[(2,5-Dihydroxyphenyl)methylene]-1,3-dihydro-2H-indol-2-one
• Description
  A specific non-ATP competitive Aurora A kinase inhibitor. Does not significantly inhibit Aurora B kinase in mammalian cells. Reduces localization of pAurora A on spindle microtubules (MTs), affects centrosome integrity, spindle formation and length and MT dynamics in interphase.
• CAS Number
  1148118-92-6
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₁₅H₁₁NO₃
• Molecular Weight
  253.25
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO
• Handling
  Protect from air and light
• Tag Line
  An Aurora kinase A inhibitor
• Storage Condition
  -20 ̊C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• SMILES
  OC1=CC=C(O)C=C1/C=C(C2=C(N3)C=CC=C2)\C3=O
• InChi
  InChI=1S/C15H11NO3/c17-10-5-6-14(18)9(7-10)8-12-11-3-1-2-4-13(11)16-15(12)19/h1-8,17-18H,(H,16,19)/b12-8-
• InChi Key
  OMKSBDLWMROKNU-WQLSENKSSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  Tripolin  
• Short name
  Tripolin A
• Alternative name
  Tripolin A

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