Ivachtin

• Catalog number
  2788-5
• Price
  Please ask
• Size
  5 mg

• Alternative_name
  2-(4-methyl-8-morpholin-4-ylsulfonyl-1,3-dioxopyrrolo[3,4-c]quinolin-2-yl)ethyl acetate
• Description
  Ivachtin is a potent, reversible and non-competitive inhibitor of caspase-3 (IC₅₀ = 23 nM) that displays 10-100 fold selectivity over other caspases. Exhibits antiapoptotic activity in human Jurkat T cells treated with staurosporine; exhibits a higher level of protection than Z-VAD-FMK (Cat. Nos. 1010 and 1140).
• CAS Number
  745046-84-8
• Structure Available
  Y
• Salt Form
  No
• Molecular Formula
  C₂₀H₂₁N₃O₇S
• Molecular Weight
  447.46
• Cell Permeable
  Y
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO (>4 mg/ml)
• Handling
  Protect from air and light
• Tag Line
  A caspase-3 inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  Gel Pack
• Shelf Life
  36 months
• MDL Number
  MFCD09971108
• PubChem CID
  11201705
• PubChem CID Link
• SMILES
  CC1=C2C(=C3C=C(C=CC3=N1)S(=O)(=O)N4CCOCC4)C(=O)N(C2=O)CCOC(=O)C
• InChi
  InChI=1S/C20H21N3O7S/c1-12-17-18(20(26)23(19(17)25)7-10-30-13(2)24)15-11-14(3-4-16(15)21-12)31(27,28)22-5-8-29-9-6-22/h3-4,11H,5-10H2,1-2H3
• InChi Key
  CC1=C2C(=C3C=C(C=CC3=N1)S(=O)(=O)N4CCOCC4)C(=O)N(C2=O)CCOC(=O)C
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  Ivachtin  
• Short name
  Ivachtin
• Alternative name
  Ivachtin

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