AMMC iodide

• Catalog number
  2873-25
• Price
  Please ask
• Size
  25 mg

• Alternative_name
  3-[2-(N,N-diethyl-N-methylammonium)ethyl]-7-methoxy-4-methylcoumarin iodide
• Description
  AMMC iodide is a useful substrate for the human cytochrome P450 CYP2D6 isozyme. It is demethylated to the fluorescent product 3-[2-(N,N-diethyl-N-methyl ammonium)ethyl]-7-hydroxy-4-methylcoumarin (AMHC). After the AMMC is hydrolyzed, the pH is increased by addition of base for optimal fluorescence detection. AMMC has been used with human liver microsomes to determine CYP2D6 activity and inhibition.
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₁₈H₂₆INO₃
• Molecular Weight
  431.31
• Cell Permeable
  No
• Purity
  ≥98% by NMR
• Solubilities
  Acetonitrile
• Handling
  Protect from air and light
• Tag Line
  A useful substrate for human cytochrome P450 CYP2D6
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• MDL Number
  MFCD13184322
• PubChem CID
  15487105
• PubChem CID Link
• SMILES
  CC[N+](C)(CC)CCC1=C(C2=C(C=C(C=C2)OC)OC1=O)C.[I-]
• InChi
  InChI=1S/C18H26NO3.HI/c1-6-19(4,7-2)11-10-16-13(3)15-9-8-14(21-5)12-17(15)22-18(16)20;/h8-9,12H,6-7,10-11H2,1-5H3;1H/q+1;/p-1
• InChi Key
  OAQIUABCTPFMOC-UHFFFAOYSA-M
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  AMMC   iodide  
• Short name
  AMMC iodide
• Alternative name
  AMMC iodide

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