Tropodithietic Acid

• Catalog number
  B1867-1
• Price
  Please ask
• Size
  1 mg

• Alternative_name
  3-Oxo-8,9-dithiabicyclo[5.2.0]nona-1,4,6-triene-2-carboxylic acid
• Description
  Tropodithietic acid is a broad spectrum tropolone antibiotic with activity against both Gram-negative and Gram-positive bacteria. Displays cytotoxic effects on mammalian cell lines (neuronal N2a cells and OLN-93 cells as model systems for nerve cells and glia) acting via disruption of mitochondrial membrane potential, activation of ERK1/2 and induction of HSP32/HO-1 (considered as a sensor of oxidative stress). A broad-spectrum antibiotic agent produced by marine bacteria which does not appear to induce resistance after long-term exposure.
• CAS Number
  750590-18-2
• Structure Available
  Yes
• Molecular Formula
  C₈H₄O₃S₂
• Molecular Weight
  212.3
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO (~5 mg/ml)
• Handling
  Protect from air and light
• Tag Line
  A broad spectrum tropolone antibiotic with activity against both Gram-negative and Gram-positive bacteria
• Storage Condition
  -20°C
• Shipping Condition
  Gel Pack
• Shelf Life
  36 months
• PubChem CID
  44632924
• PubChem CID Link
• SMILES
  C1=CC(=O)C(=C2C(=C1)SS2)C(=O)O
• InChi
  InChI=1S/C8H4O3S2/c9-4-2-1-3-5-7(13-12-5)6(4)8(10)11/h1-3H,(H,10,11)
• InChi Key
  BLFCMITWMARUSM-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  Tropodithietic   Acid  
• Short name
  Tropodithietic Acid
• Alternative name
  Tropodithietic Acid

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