Autophinib

• Catalog number
  B2260-5
• Price
  Please ask
• Size
  5 mg

• Alternative_name
  6-Chloro-N-(5-methyl-1H-pyrazol-3-yl)-2-(4-nitrophenoxy)-pyrimidinamine
• Description
  Autophinib is a potent autophagy inhibitor. It inhibits autophagy induced by starvation or rapamycin by targeting the lipid kinase VPS34 with IC50s of 90, 40 and 19 nM, respectively.
• CAS Number
  1644443-47-9
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₁₄H₁₁ClN₆O₃
• Molecular Weight
  346.73
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO (>6 mg/ml)
• Handling
  Protect from air and light
• Tag Line
  A potent autophagy inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• PubChem CID
  129626605
• PubChem CID Link
• SMILES
  CC1=CC(=NN1)NC2=CC(=NC(=N2)OC3=CC=C(C=C3)[N+](=O)[O-])Cl
• InChi
  InChI=1S/C14H11ClN6O3/c1-8-6-13(20-19-8)17-12-7-11(15)16-14(18-12)24-10-4-2-9(3-5-10)21(22)23/h2-7H,1H3,(H2,16,17,18,19,20)
• InChi Key
  CEUMAXLRGBKFQP-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  YES

• Gene target
  Autophinib  
• Short name
  Autophinib
• Alternative name
  Autophinib

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