NCKAP1 Antibody, ALEXA FLUOR 488

• Catalog number
  bs-6204R-A488
• Price
  Please ask
• Size
  100ul

• Long name
  NCKAP1 Polyclonal Antibody, ALEXA FLUOR 488 Conjugated
• Also known as
  Anti-NCKAP1 PAb ALEXA FLUOR 488
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 488
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  NCKAP1
• Specificity
  This is a highly specific antibody against NCKAP1.
• Modification
  Unmodified
• Modification Site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human 12 NCKAP1
• Gene ID Number
  10787
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  NAP125, also known as NCKAP1 (NCK-associated protein 1), p125Nap1 or membrane-associated protein HEM-2, is a 1,128 amino acid single pass membrane protein that exists as two alternatively spliced isoforms and belongs to the HEM-1/HEM-2 family. While widely expressed, NAP125 is found at highest levels in heart, brain and skeletal muscle where it regulates Rac-dependent actin remodeling as part of a lamellipodial complex with WAVE2, Abi-1 and CYFIP1. NAP125 localizes to the cytoplasmic side of lamellipodium membrane and is encoded by a gene that maps to human chromosome 2q32.1 and mouse chromosome 2 C3. NAP125 expression is markedly reduced in Alzheimer disease (AD)-affected brains, suggesting a possible role in the disease.
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  499nm/519nm
• Synonyms
  NCK associated protein 1; NCK associated protein 1; Membrane associated protein HEM2; Membrane-associated protein HEM-2; NAP 1; NAP1; NAP125; NCK associated protein; Nck-associated protein 1; Nckap1; NCKP1_HUMAN; p125Nap1.
• Properties
  For facs or microscopy Alexa 1 conjugate. Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), yet the Anti-NCKAP1 has a very high photo stability. As a result of this photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry. It is distinguished in the FL1 of a FACS-Calibur or FACScan. Also Alexa Fluor 488 is pH stable. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor
• French translation
  anticorps

• Gene target
  NCKAP1  
• Gene symbol
  NCKAP1
• Short name
  Anti-NCKAP1
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 488
• Alternative name
  NCKAP1 Polyclonal Antibody, ALEXA FLUOR 488
• Alternative technique
  antibodies
• Alternative to gene target
  NCK-associated protein 1, HEM2 and NAP1 and NAP125 and p125Nap1, NCKAP1 and IDBG-76903 and ENSG00000061676 and 10787, Rac GTPase binding, Plasma membranes, Nckap1 and IDBG-183835 and ENSMUSG00000027002 and 50884, NCKAP1 and IDBG-639791 and ENSBTAG00000033662 and 100300817,101907541

Gene info

• Identity
  HGNC:7666
• Gene
  NCKAP1
• Long gene name
  NCK associated protein 1
• Synonyms
  • Nap1
  • HEM2
  • NAP125
• GenBank acession
  • AB014509
• Locus
  2q32.1
• Discovery year
  1999-07-19
• Entrez gene record
  10787
• Pubmed identfication
  • 10673335
  • 12181570
  • 9344857
• RefSeq identity
  • NM_205842
• Classification
  • SCAR/WAVE complex
• VEGA ID
  OTTHUMG00000132623

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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