Meisoindigo
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Catalog numberB1822-25
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PricePlease ask
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Size25 mg
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Alternative_name(E)-1,1'-dimethyl-[3,3'-biindolinylidene]-2,2'-dione; Methyl isoindigotin; N-Methylisoindigotin; Meisoindigo; Dian III
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DescriptionMeisoindigo is a synthetic derivative of indirubin that acts as a potential agent for acute myeloid leukemia. In the in vitro assay, it can inhibit synthesis of DNA and RNA and the assembly of microtubules. It is also reported to have efficacy in acute myeloid leukemia. In the AML cell lines, HL-60, NB4 and U937, meisoindigo induces apoptosis in both caspase-dependent and -independent pathways.
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CAS Number97207-47-1
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Structure AvailableYes
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Molecular FormulaC₁₇H₁₂N₂O₂
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Molecular Weight276.29
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Cell PermeableYes
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Purity≥98% by HPLC
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SolubilitiesDMSO
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HandlingProtect from air and light
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Tag LineAn anticancer agent
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Storage Condition-20°C
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Shipping ConditionGel Pack
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Shelf Life36 months
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PubChem CID5479433
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SMILESCN1C2=CC=CC=C2C(=C3C4=CC=CC=C4NC3=O)C1=O
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InChiInChI=1S/C17H12N2O2/c1-19-13-9-5-3-7-11(13)15(17(19)21)14-10-6-2-4-8-12(10)18-16(14)20/h2-9H,1H3,(H,18,20)/b15-14+
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InChi KeyQNOCRUSVMMAKSC-CCEZHUSRSA-N
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MSDS AvailableYes
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Gene target
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Short nameMeisoindigo
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Alternative nameMeisoindigo
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