Meisoindigo

• Catalog number
  B1822-5
• Price
  Please ask
• Size
  5 mg

• Alternative_name
  (E)-1,1'-dimethyl-[3,3'-biindolinylidene]-2,2'-dione; Methyl isoindigotin; N-Methylisoindigotin; Meisoindigo; Dian III
• Description
  Meisoindigo is a synthetic derivative of indirubin that acts as a potential agent for acute myeloid leukemia. In the in vitro assay, it can inhibit synthesis of DNA and RNA and the assembly of microtubules. It is also reported to have efficacy in acute myeloid leukemia. In the AML cell lines, HL-60, NB4 and U937, meisoindigo induces apoptosis in both caspase-dependent and -independent pathways.
• CAS Number
  97207-47-1
• Structure Available
  Yes
• Molecular Formula
  C₁₇H₁₂N₂O₂
• Molecular Weight
  276.29
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO
• Handling
  Protect from air and light
• Tag Line
  An anticancer agent
• Storage Condition
  -20°C
• Shipping Condition
  Gel Pack
• Shelf Life
  36 months
• PubChem CID
  5479433
• PubChem CID Link
• SMILES
  CN1C2=CC=CC=C2C(=C3C4=CC=CC=C4NC3=O)C1=O
• InChi
  InChI=1S/C17H12N2O2/c1-19-13-9-5-3-7-11(13)15(17(19)21)14-10-6-2-4-8-12(10)18-16(14)20/h2-9H,1H3,(H,18,20)/b15-14+
• InChi Key
  QNOCRUSVMMAKSC-CCEZHUSRSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  Meisoindigo  
• Short name
  Meisoindigo
• Alternative name
  Meisoindigo

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