Granzyme B Antibody

• Catalog number
  6683-100
• Price
  Please ask
• Size
  100 μg

• Antibody Target
  Granzyme B
• Target Alternative Name
  C11, CTLA-1, Cathepsin G-like 1, CGL1, CSPB, CTLA1, GRB
• Antibody Type
  Polyclonal
• Species Reactivities
  Human, mouse, rat
• Accession
  P10144
• Gene Id
  3002
• Appearance
  Colorless liquid
• Form
  Liquid
• Concentration
  0.5 mg/ml
• Formulation
  100 µg (0.5 mg/ml) of antibody in PBS pH 7.2 containing 0.01 % BSA, 50 % glycerol and 0.3 % ProClin®
• Purification
  Affinity Purified Antibody
• Application
  Western blot
• Positive Control
  Western Blot: mouse muscle lysate, rat kidney lysate, recombinant protein
• Application And Usages
  Western blot: 1-4 µg
• Description
  This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.
• Storage Condition
  -20 °C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans.
• Handling
  The antibody solution should be gently mixed before use.
• Western Blot Verified
  Verified
• Immunocytochemistry Verified
  Not Verified
• Immunofluorescence Verified
  Not Verified
• Immunoprecipitation Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Dot Blot Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Granzyme  
• Gene symbol
  GZMB
• Short name
  Granzyme B Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Granzyme B (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:4709
• Gene
  GZMB
• Long gene name
  granzyme B
• Synonyms gene
  • CTLA1
  • CSPB
• Synonyms gene name
  • granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
• Synonyms
  • CCPI
  • CGL-1
  • CSP-B
  • CGL1
  • CTSGL1
  • HLP
  • SECT
• Synonyms name
  • fragmentin 2
  • cytotoxic serine protease B
  • cathepsin G-like 1
  • T-cell serine protease 1-3E
  • granzyme 2
  • cytotoxic T-lymphocyte-associated serine esterase 1
• GenBank acession
  • BC030195
• Locus
  14q12
• Discovery year
  1989-05-12
• Entrez gene record
  3002
• Pubmed identfication
  • 2323780
• RefSeq identity
  • NM_004131
• Classification
  • Granule associated serine proteases of immune defence
• VEGA ID
  OTTHUMG00000029369

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Product images

Similar products