Pluripotin

• Catalog number
  2165-1
• Price
  Please ask
• Size
  1 mg

• Alternative_name
  N-​(3-​(7-​(1,​3-​dimethyl-​1H-​pyrazol-​5-​ylamino)-​1-​methyl-​2-​oxo- ​1,​2-​dihydropyrimido[4,​5-​d]pyrimidin-​3(4H)-​yl)-​4-​methylphenyl)-​ 3-​(trifluoromethyl)benzamide; SC1
• Description
  Pluripotin (SC1) regulates mouse embryonic stem cell (ESC) self-renewal. It was shown that SC1 is sufficient for sustaining long-term self-renewal of mouse ES cells in an undifferentiated state in the absence of LIF, feeder cells, or serum. SC1 acts through dual inhibition of Ras-GAP and ERK1 with Kd values of 98 and 212 nM, respectively.
• CAS Number
  839707-37-8
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₂₇H₂₅F₃N₈O₂
• Molecular Weight
  550.54
• Cell Permeable
  Yes
• Purity
  ≥97% by HPLC
• Solubilities
  DMSO (100 mM)
• Handling
  Protect from air and light
• Tag Line
  A regulator of mouse embryonic stem cell (ESC) self-renewal
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  24months
• MDL Number
  MFCD20527253
• PubChem CID
  12003241
• PubChem CID Link
• SMILES
  CC1=C(C=C(C=C1)NC(=O)C2=CC(=CC=C2)C(F)(F)F)N3CC4=CN=C(N=C4N(C3=O)C)NC5=CC(=NN5C)C
• InChi
  InChI=1S/C27H25F3N8O2/c1-15-8-9-20(32-24(39)17-6-5-7-19(11-17)27(28,29)30)12-21(15)38-14-18-13-31-25(34-23(18)36(3)26(38)40)33-22-10-16(2)35-37(22)4/h5-13H,14H2,1-4H3,(H,32,39)(H,31,33,34)
• InChi Key
  NBZFRTJWEIHFPF-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  Pluripotin  
• Short name
  Pluripotin
• Alternative name
  Pluripotin

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