Hygromycin B

• Catalog number
  2589-1000
• Price
  Please ask
• Size
  1 g

• Alternative_name
  (3'R,3aS,4S,4'R,5'R,6R,6'R,7S,7aS)-4-[(1R,2S,3R,5S,6R)-3-amino-2,6-dihydroxy-5-(methylamino)cyclohexyl]oxy-6'-[(1S)-1-amino-2-hydroxyethyl]-6-(hydroxymethyl)spiro[4,6,7,7a-tetrahydro-3aH-[1,3]dioxolo[4,5-c]pyran-2,2'-oxane]-3',4',5',7-tetrol
• Description
  Hygromycin B is an aminoglycoside antibiotic produced by Streptomyces hygroscopicus that is routinely used as a selection agent for cells that contain hph or hyg Hygromycin resistant gene. Hygromycin B is thought to inhibit protein synthesis by strengthening the interaction of peptidyl-tRNA in the ribosomal acceptor (“A”) site thereby preventing translocation of by EF-2 (elongation Factor-2). Hygromycin B is effective on most bacteria, fungi and higher eukaryotes.
• CAS Number
  31282-04-9
• Structure Available
  Y
• Salt Form
  No
• Molecular Formula
  C₂₀H₃₇N₃O₃
• Molecular Weight
  527.52
• Cell Permeable
  No
• Purity
  ≥90% by HPLC
• Solubilities
  H₂O (~ 50 mg/ml)
• Handling
  Protect from light and moisture
• Tag Line
  An antibiotic and a selection agent
• Storage Condition
  2-8ºC
• Shipping Condition
  Gel pack
• Shelf Life
  36 months
• MDL Number
  MFCD06795479
• PubChem CID
  35766
• PubChem CID Link
• SMILES
  CNC1CC(C(C(C1O)OC2C3C(C(C(O2)CO)O)OC4(O3)C(C(C(C(O4)C(CO)N)O)O)O)O)N
• InChi
  InChI=1S/C20H37N3O13/c1-23-7-2-5(21)9(26)15(10(7)27)33-19-17-16(11(28)8(4-25)32-19)35-20(36-17)18(31)13(30)12(29)14(34-20)6(22)3-24/h5-19,23-31H,2-4,21-22H2,1H3/t5-,6+,7+,8-,9+,10-,11+,12-,13-,14-,15-,16+,17+,18-,19+,20?/m1/s1
• InChi Key
  GRRNUXAQVGOGFE-KPBUCVLVSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  Hygromycin  
• Short name
  Hygromycin B
• Alternative name
  Hygromycin B

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