AC710
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Catalog number2884-5
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PricePlease ask
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Size5 mg
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Alternative_nameN-(4-(3-(5-(tert-butyl)isoxazol-3-yl)ureido)phenyl)-5-((1-ethyl-2,2,6,6-tetramethylpiperidin-4-yl)oxy)picolinamide
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DescriptionAC710 is a potent, and selective PDGFR-family kinases inhibitor with Kd values of 0.6 nM,1.0 nM, 1.3 nM and 1.0 nM for FLT3, KIT, PDGFRα and PDGFRβ respectively. Displays potent anticancer activity.
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CAS Number1351522-04-7
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Structure AvailableYes
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Salt FormNo
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Molecular FormulaC₃₁H₄₂N₆O₄
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Molecular Weight562.7
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Cell PermeableYes
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Purity≥98% by HPLC
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SolubilitiesDMSO
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HandlingProtect from air and light
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Tag LineA potent PDGFR-family kinases inhibitor
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Storage Condition-20°C
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Shipping Conditiongel pack
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Shelf Life36 months
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PubChem CID54760053
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SMILESCCN1C(CC(CC1(C)C)OC2=CN=C(C=C2)C(=O)NC3=CC=C(C=C3)NC(=O)NC4=NOC(=C4)C(C)(C)C)(C)C
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InChiInChI=1S/C31H42N6O4/c1-9-37-30(5,6)17-23(18-31(37,7)8)40-22-14-15-24(32-19-22)27(38)33-20-10-12-21(13-11-20)34-28(39)35-26-16-25(41-36-26)29(2,3)4/h10-16,19,23H,9,17-18H2,1-8H3,(H,33,38)(H2,34,35,36,39)
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InChi KeyJVCWPUFNLFSKFS-UHFFFAOYSA-N
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MSDS AvailableYes
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Gene target
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Short nameAC710
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Alternative nameAC710
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