AC710

  • Catalog number
    2884-5
  • Price
    Please ask
  • Size
    5 mg
  • Alternative_name
    N-(4-(3-(5-(tert-butyl)isoxazol-3-yl)ureido)phenyl)-5-((1-ethyl-2,2,6,6-tetramethylpiperidin-4-yl)oxy)picolinamide
  • Description
    AC710 is a potent, and selective PDGFR-family kinases inhibitor with Kd values of 0.6 nM,1.0 nM, 1.3 nM and 1.0 nM for FLT3, KIT, PDGFRα and PDGFRβ respectively. Displays potent anticancer activity.
  • CAS Number
    1351522-04-7
  • Structure Available
    Yes
  • Salt Form
    No
  • Molecular Formula
    C₃₁H₄₂N₆O₄
  • Molecular Weight
    562.7
  • Cell Permeable
    Yes
  • Purity
    ≥98% by HPLC
  • Solubilities
    DMSO
  • Handling
    Protect from air and light
  • Tag Line
    A potent PDGFR-family kinases inhibitor
  • Storage Condition
    -20°C
  • Shipping Condition
    gel pack
  • Shelf Life
    36 months
  • PubChem CID
    54760053
  • SMILES
    CCN1C(CC(CC1(C)C)OC2=CN=C(C=C2)C(=O)NC3=CC=C(C=C3)NC(=O)NC4=NOC(=C4)C(C)(C)C)(C)C
  • InChi
    InChI=1S/C31H42N6O4/c1-9-37-30(5,6)17-23(18-31(37,7)8)40-22-14-15-24(32-19-22)27(38)33-20-10-12-21(13-11-20)34-28(39)35-26-16-25(41-36-26)29(2,3)4/h10-16,19,23H,9,17-18H2,1-8H3,(H,33,38)(H2,34,35,36,39)
  • InChi Key
    JVCWPUFNLFSKFS-UHFFFAOYSA-N
  • MSDS Available
    Yes
  • Gene target
    AC710  
  • Short name
    AC710
  • Alternative name
    AC710
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