BI-78D3
-
Catalog numberB1686-5
-
PricePlease ask
-
Size5 mg
-
-
Alternative_nameBI-78D3; BI78D3; BI 78D3; 4-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-5-((5-nitrothiazol-2-yl)thio)-4H-1,2,4-triazol-3-ol; 4-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-[(5-nitro-1,3-thiazol-2-yl)sulfanyl]-1H-1,2,4-triazol-5-one
-
DescriptionBI 78D3 is a competitive c-Jun N-terminal kinase (JNK) inhibitor with IC50 of 280 nM that displays > 100 fold selectivity over p38α and no activity at mTOR and PI-3K.
-
CAS Number883065-90-5
-
Structure AvailableYes
-
Salt FormNo
-
Molecular FormulaC₁₃H₉N₅O₅S₂
-
Molecular Weight379.37
-
Cell PermeableYes
-
Purity>98%
-
SolubilitiesDMSO
-
HandlingProtect from air and light
-
Tag LineA competitive JNK inhibitor
-
Storage Condition-20°C
-
Shipping Conditiongel pack
-
Shelf Life36 months
-
MDL NumberMFCD01313575
-
PubChem CID2747117
-
SMILESC1COC2=C(O1)C=CC(=C2)N3C(=O)NN=C3SC4=NC=C(S4)[N+](=O)[O-]
-
InChiInChI=1S/C13H9N5O5S2/c19-11-15-16-12(25-13-14-6-10(24-13)18(20)21)17(11)7-1-2-8-9(5-7)23-4-3-22-8/h1-2,5-6H,3-4H2,(H,15,19)
-
InChi KeyQFRLDZGQEZCCJZ-UHFFFAOYSA-N
-
MSDS AvailableYes
-
Gene target
-
Gene symbolTMBIM6, SCARB1
-
Short nameBI-78D3
-
Alternative nameBI-78D3
-
Gene info
-
Identity
-
Gene
-
Long gene nametransmembrane BAX inhibitor motif containing 6
-
Synonyms gene
-
Synonyms gene name
- testis enhanced gene transcript
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year1994-08-30
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Transmembrane BAX inhibitor motif containing
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene namescavenger receptor class B member 1
-
Synonyms gene
-
Synonyms gene name
- CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 1
- scavenger receptor class B, member 1
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year1994-09-06
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Scavenger receptors
-
VEGA ID