Elvitegravir

  • Catalog number
    9465-25
  • Price
    Please ask
  • Size
    25 mg
  • Alternative_name
    6-[(3-chloro-2-fluorophenyl)methyl]-1-[(2S)-1-hydroxy-3-methylbutan-2-yl]-7-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; EVG, JTK-303/GS-9137
  • Description
    Elvitegravir is a novel HIV-1 integrase inhibitor that blocks strand transfer by the viral enzyme. It displays an IC₅₀ of 7.2 nM in the strand transfer assay, and shows an EC₅₀ of 0.9 nM in an acute HIV-1 infection assay.
  • CAS Number
    697761-98-1
  • Structure Available
    Yes
  • Molecular Formula
    C₂₃H₂₃ClFNO₅
  • Molecular Weight
    447.88
  • Cell Permeable
    Yes
  • Purity
    ≥98% by HPLC
  • Solubilities
    DMSO (>50 mg/ml)
  • Handling
    Protect from air and light
  • Tag Line
    A HIV-1 integrase inhibitor
  • Storage Condition
    -20°C
  • Shipping Condition
    Gel pack
  • Shelf Life
    36 months
  • PubChem CID
    5277135
  • SMILES
    CC(C)C(CO)N1C=C(C(=O)C2=CC(=C(C=C21)OC)CC3=C(C(=CC=C3)Cl)F)C(=O)O
  • InChi
    InChI=1S/C23H23ClFNO5/c1-12(2)19(11-27)26-10-16(23(29)30)22(28)15-8-14(20(31-3)9-18(15)26)7-13-5-4-6-17(24)21(13)25/h4-6,8-10,12,19,27H,7,11H2,1-3H3,(H,29,30)/t19-/m1/s1
  • InChi Key
    JUZYLCPPVHEVSV-LJQANCHMSA-N
  • MSDS Available
    Yes
  • Gene target
  • Short name
    Elvitegravir
  • Alternative name
    Elvitegravir
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