Elvitegravir
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Catalog number9465-25
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PricePlease ask
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Size25 mg
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Alternative_name6-[(3-chloro-2-fluorophenyl)methyl]-1-[(2S)-1-hydroxy-3-methylbutan-2-yl]-7-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; EVG, JTK-303/GS-9137
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DescriptionElvitegravir is a novel HIV-1 integrase inhibitor that blocks strand transfer by the viral enzyme. It displays an IC₅₀ of 7.2 nM in the strand transfer assay, and shows an EC₅₀ of 0.9 nM in an acute HIV-1 infection assay.
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CAS Number697761-98-1
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Structure AvailableYes
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Molecular FormulaC₂₃H₂₃ClFNO₅
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Molecular Weight447.88
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Cell PermeableYes
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Purity≥98% by HPLC
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SolubilitiesDMSO (>50 mg/ml)
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HandlingProtect from air and light
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Tag LineA HIV-1 integrase inhibitor
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Storage Condition-20°C
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Shipping ConditionGel pack
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Shelf Life36 months
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PubChem CID5277135
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SMILESCC(C)C(CO)N1C=C(C(=O)C2=CC(=C(C=C21)OC)CC3=C(C(=CC=C3)Cl)F)C(=O)O
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InChiInChI=1S/C23H23ClFNO5/c1-12(2)19(11-27)26-10-16(23(29)30)22(28)15-8-14(20(31-3)9-18(15)26)7-13-5-4-6-17(24)21(13)25/h4-6,8-10,12,19,27H,7,11H2,1-3H3,(H,29,30)/t19-/m1/s1
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InChi KeyJUZYLCPPVHEVSV-LJQANCHMSA-N
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MSDS AvailableYes
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Gene target
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Short nameElvitegravir
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Alternative nameElvitegravir
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