Cobicistat

• Catalog number
  9474-25
• Price
  Please ask
• Size
  25 mg

• Alternative_name
  1,3-thiazol-5-ylmethyl N-[(2R,5R)-5-[[(2S)-2-[[methyl-[(2-propan-2-yl-1,3-thiazol-4-yl)methyl]carbamoyl]amino]-4-morpholin-4-ylbutanoyl]amino]-1,6-diphenylhexan-2-yl]carbamate; GS-9350
• Description
  Cobicistat (GS-9350) is a potent, and selective inhibitor of human cytochrome P450 3A (CYP3A) enzymes (Ki = 939 nM). Acts as a pharmacoenhancing or "boosting" agent for antiviral drugs used in the treatment of HIV infection.
• CAS Number
  1004316-88-4
• Structure Available
  Yes
• Molecular Formula
  C₄₀H₅₃N₇O₅S₂
• Molecular Weight
  776.02
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO (~8 mg/ml)
• Handling
  Protect from air and light
• Tag Line
  A potent, and selective inhibitor of human cytochrome P450 3A (CYP3A) enzymes
• Storage Condition
  -20°C
• Shipping Condition
  Gel pack
• Shelf Life
  36 months
• PubChem CID
  25151504
• PubChem CID Link
• SMILES
  CC(C)C1=NC(=CS1)CN(C)C(=O)NC(CCN2CCOCC2)C(=O)NC(CCC(CC3=CC=CC=C3)NC(=O)OCC4=CN=CS4)CC5=CC=CC=C5
• InChi
  InChI=1S/C40H53N7O5S2/c1-29(2)38-43-34(27-53-38)25-46(3)39(49)45-36(16-17-47-18-20-51-21-19-47)37(48)42-32(22-30-10-6-4-7-11-30)14-15-33(23-31-12-8-5-9-13-31)44-40(50)52-26-35-24-41-28-54-35/h4-13,24,27-29,32-33,36H,14-23,25-26H2,1-3H3,(H,42,48)(H,44,50)(H,45,49)/t32-,33-,36+/m1/s1
• InChi Key
  ZCIGNRJZKPOIKD-CQXVEOKZSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  Cobicistat  
• Short name
  Cobicistat
• Alternative name
  Cobicistat

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