TGF-β3, Mouse Recombinant

• Catalog number
  7588-50
• Price
  Please ask
• Size
  50 ug

• Synonyms
  Transforming growth factor beta-3
• Alternative_names
  Transforming growth factor beta-3
• Description
  Plays an important role in wound repair/scarring, osteoblast proliferation, chemotaxis, and collagen synthesis
• Recombinant
  Yes
• Source
  E. coli
• Purity by SDS PAGE
  ≥98%
• Assay
  SDS-PAGE
• Endotoxin Level
  Measured by kinetic LAL analysis and is typically ≤ 1 EU/ug protein
• Activity Specifications test method
  The activity is determined by the cell toxicity assay, using the WHO Standard 98/608 as a direct comparison, and is typically less than 0.05 ng/mL.
• Biological activity
  The activity is determined by the cell toxicity assay, using the WHO Standard 98/608 as a direct comparison, and is typically less than 0.05 ng/mL.
• Molecular Weight
  25.5 kDa.
• Storage Temp
  4°C
• Shipping
  Gel Pack
• Shelf Life
  12 months
• Concentration
  0.25 mg/ml
• Appearance
  Liquid
• Physical form description
  0.25 mg/mL solution containing 20% ethanol and 0.12% acetic acid (AcOH)
• Background Information
  The Transforming Growth Factors (TGFs) are multifunctional peptides that regulate growth and differentiation in a variety of cells. Recent data suggests that individual TGF-β isoforms (TGF-β1, -β2 and –β3) have overlapping, yet distinct biological actions and target cell specificities, both in developing and adult tissues. TGF-β3 is a new isoform that is presumed to play an important role in wound repair and scarring. TGF-β3 is also thought to be involved in osteoblast proliferation, chemotaxis, and collagen synthesis. Recombinant mouse TGF-β3 is a non-glycosylated, disulfide-linked homodimer, containing two 112 amino acid chains, with a total molecular weight of 25.5 kDa.
• Amino acid sequence
  ALDTNYCFRN LEENCCVRPL YIDFRQDLGW KWVHEPKGYY ANFCSGPCPY LRSADTTHST VLGLYNTLNP EASASPCCVP QDLEPLTILY YVGRTPKVEQ LSNMVVKSCK CS
• Handling
  Centrifuge the vial prior to opening.
• Usage
  For Research Use Only! Not to be used in humans
• Datasheet
• Test
  Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
• Latin name
  Mus musculus
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  TGF-β3  
• Gene symbol
  TAB3, TAB3P1, CSRNP3
• Short name
  TGF-β3, Mouse Recombinant
• Technique
  Recombinant, Mouse, mouses, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Host
  mouse
• Species
  Mouses
• Alternative name
  TGF-β3, Mouse Rec.
• Alternative technique
  rec, murine

Gene info

• Identity
  HGNC:30681
• Gene
  TAB3
• Long gene name
  TGF-beta activated kinase 1 (MAP3K7) binding protein 3
• Synonyms gene
  • MAP3K7IP3
• Synonyms gene name
  • mitogen-activated protein kinase kinase kinase 7 interacting protein 3
  • TGF-beta activated kinase 1/MAP3K7 binding protein 3
  • TGF-beta activated kinase 1 and MAP3K7 binding protein 3
• Synonyms name
  • TAK1 binding protein 3
• GenBank acession
  • AY331591
• Locus
  Xp21.2
• Discovery year
  2006-06-26
• Entrez gene record
  257397
• Pubmed identfication
  • 14633987
  • 14670075
• RefSeq identity
  • NM_152787
• Classification
  • Zinc fingers RANBP2-type
• VEGA ID
  OTTHUMG00000021329
• Locus Specific Databases
  • Global Variome shared LOVD

Gene info

• Identity
  HGNC:37723
• Gene
  TAB3P1
• Long gene name
  TGF-beta activated kinase 1/MAP3K7 binding protein 3 pseudogene 1
• Locus
  Yq11.221
• Discovery year
  2010-02-05
• Entrez gene record
  643199
• VEGA ID
  OTTHUMG00000036321

Gene info

• Identity
  HGNC:30729
• Gene
  CSRNP3
• Long gene name
  cysteine and serine rich nuclear protein 3
• Synonyms gene
  • FAM130A2
• Synonyms gene name
  • family with sequence similarity 130, member A2
  • cysteine-serine-rich nuclear protein 3
• Synonyms
  • FLJ32093
  • TAIP-2
  • PPP1R73
• Synonyms name
  • TGF beta induced apotosis protein 2
  • protein phosphatase 1, regulatory subunit 73
• GenBank acession
  • AB063300
• Locus
  2q24.3
• Discovery year
  2007-01-19
• Entrez gene record
  80034
• Pubmed identfication
  • 17726538
• RefSeq identity
  • NM_024969
• Classification
  • Protein phosphatase 1 regulatory subunits
• VEGA ID
  OTTHUMG00000132145

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Product images

Similar products