LKB1, phosphorylated (Ser248) (STK11,serine/threonine kinase 11,PJS, Renal carcinoma antigen NY-REN-19, Serine/threonine-protein kinase LKB1)

• Catalog number
  MBS620046
• Price
  Please ask
• Size
  0.1 mg

• Products_type
  Antibody
• Products_short_name
  [LKB1]
• Products_name_syn
  [Anti -LKB1, phosphorylated (Ser248) (STK11,serine/threonine kinase 11,PJS, Renal carcinoma antigen NY-REN-19, Serine/threonine-protein kinase LKB1)]
• Other_names
  [lkb1, isoform J; CG9374 gene product from transcript CG9374-RJ; lkb1, isoform J; CG9374-PJ; lkb1-PJ; lkb1, isoform A; CG9374-PA; lkb1-PA; lkb1, isoform E; CG9374-PE; lkb1-PE; lkb1, isoform I; CG9374-PI; lkb1-PI; lkb1, isoform D; CG9374-PD; lkb1-PD; lkb1, isoform F; CG9374-PF; lkb1-PF; lkb1, isoform B; CG9374-PB; lkb1-PB; lkb1, isoform H; CG9374-PH; lkb1-PH; lkb1, isoform C; CG9374-PC; lkb1-PC]
• Other_gene_names
  [lkb1; anon-EST:Posey135; CG9374; dlkb1; dLKB1; DmelCG9374; DmLKB1; Lkb1; LKB1; LKB1/PEUTZ JEGHERS KINASE; par-4; PAR-4; PAR4; STK11]
• Clonality
  Polyclonal
• Reactivity
  Human
• Specificity
  Recognizes endogenous human LKB1 when phosphorylated at Ser248 at ~62kD using Western blot.
• Purity
  Affinity Purified Purified by immunoaffinity chromatography.
• Form
  Lyophilized from a 0.2um sterile-filtered solution in PBS with 5% trehalose.
• Storage_stability
  Lyophilized samples are stable for twelve months from date of receipt when stored at -20 degree C to -70 degree C. Upon reconstitution, the antibody can be stored at 2 degree -8 degree C for 1 month without detectable loss of activity. Reconstituted antibody can also be aliquotted and stored frozen at -20 degree C to -70 degree C in a manual defrost freezer for six months without detectable loss of activity. Avoid repeated freeze-thaw cycles.
• Tested_application
  Western Blot (WB)
• Description
  Antigens are peptides or recombinant or native dependent on the production method. Serine protease, D- or L-serine arginine rich enzyme of serine threonine kinase with serine that is encoded by the codons UCU, UCC, UCA, UCG, AGU and AGC is an ɑ-amino acid that is used in the biosynthesis of proteins. It contains an α-amino group (which is in the protonated −NH+ 3 form under biological conditions), a carboxyl group. It is non-essential in humans, meaning the body can synthesize it.

• Gene target
  LKB1   phosphorylated   Ser248   STK11   serine/threonine   kinase   PJS   Renal   carcinoma   NY-REN-19   Serine/threonine-protein   kinase   LKB1  
• Gene symbol
  STK11, IRAK4, KCTD3, FAM153A, MED6, ANKRD13A, NEK1, CEP83, ZC3H14, PHF11
• Short name
  LKB1, phosphorylated (Ser248) (STK11 serine/threonine kinase 11 PJS, Renal carcinoma antigen NY-REN-19, Serine/threonine-protein kinase LKB1)
• Technique
  antigen, antigenes
• Host
  Rabbit
• Isotype
  IgG
• Alternative name
  LKB1, phosphorylated (Ser248) (STK11,serine/threonine phosphorylation catalyst 11,PJS, Renal carcinoma protein NY-REN-19, Serine/threonine-protein phosphorylation catalyst LKB1)
• Alternative technique
  antigenes
• Tissue
  carcinoma

Gene info

• Identity
  HGNC:11389
• Gene
  STK11
• Long gene name
  serine/threonine kinase 11
• Synonyms gene name
  • serine/threonine kinase 11 (Peutz-Jeghers syndrome)
• Synonyms
  • PJS
  • LKB1
• Synonyms name
  • polarization-related protein LKB1
• GenBank acession
  • U63333
• Locus
  19p13.3
• Discovery year
  1998-01-21
• Entrez gene record
  6794
• Pubmed identfication
  • 9425897
• RefSeq identity
  • NM_000455
• VEGA ID
  OTTHUMG00000180118
• Locus Specific Databases
  • LRG_319

Gene info

• Identity
  HGNC:17967
• Gene
  IRAK4
• Long gene name
  interleukin 1 receptor associated kinase 4
• Synonyms
  • NY-REN-64
• GenBank acession
  • AF155118
• Locus
  12q12
• Discovery year
  2002-09-27
• Entrez gene record
  51135
• Pubmed identfication
  • 3772297
  • 10508479
• VEGA ID
  OTTHUMG00000169425
• Locus Specific Databases
  • IRAK4base: Mutation registry for IRAK4 deficiency
  • LRG_75

Gene info

• Identity
  HGNC:21305
• Gene
  KCTD3
• Long gene name
  potassium channel tetramerization domain containing 3
• Synonyms gene name
  • potassium channel tetramerisation domain containing 3
• Synonyms
  • NY-REN-45
• GenBank acession
  • AK024547
• Locus
  1q41
• Discovery year
  2003-06-03
• Entrez gene record
  51133
• Pubmed identfication
  • 10508479
• RefSeq identity
  • NM_016121
• Classification
  • WD repeat domain containing
  • KCTD family
• VEGA ID
  OTTHUMG00000037019

Gene info

• Identity
  HGNC:29940
• Gene
  FAM153A
• Long gene name
  family with sequence similarity 153 member A
• Synonyms gene name
  • family with sequence similarity 153, member A
• Synonyms
  • NY-REN-7
• Synonyms name
  • NY REN 7 antigen
• GenBank acession
  • AB018295
• Locus
  5q35.3
• Discovery year
  2008-01-09
• Entrez gene record
  285596
• Pubmed identfication
  • 10508479
  • 9872452
• RefSeq identity
  • NM_173663
• VEGA ID
  OTTHUMG00000163394

Gene info

• Identity
  HGNC:19970
• Gene
  MED6
• Long gene name
  mediator complex subunit 6
• Synonyms gene name
  • mediator of RNA polymerase II transcription, subunit 6 homolog (S. cerevisiae)
• Synonyms
  • NY-REN-28
• GenBank acession
  • BC004106
• Locus
  14q24.2
• Discovery year
  2002-12-09
• Entrez gene record
  10001
• Pubmed identfication
  • 9234719
  • 9671713
• RefSeq identity
  • NM_005466
• Classification
  • Mediator complex
• VEGA ID
  OTTHUMG00000171252

Gene info

• Identity
  HGNC:21268
• Gene
  ANKRD13A
• Long gene name
  ankyrin repeat domain 13A
• Synonyms gene
  • ANKRD13
• Synonyms gene name
  • ankyrin repeat domain 13
• Synonyms
  • NY-REN-25
• GenBank acession
  • AF064604
• Locus
  12q24.11
• Discovery year
  2003-06-05
• Entrez gene record
  88455
• Pubmed identfication
  • 10508479
• RefSeq identity
  • NM_033121
• Classification
  • Ankyrin repeat domain containing
• VEGA ID
  OTTHUMG00000169314

Gene info

• Identity
  HGNC:7744
• Gene
  NEK1
• Long gene name
  NIMA related kinase 1
• Synonyms gene name
  • NIMA (never in mitosis gene a)-related kinase 1
• Synonyms
  • NY-REN-55
  • KIAA1901
• GenBank acession
  • AB067488
• Locus
  4q33
• Discovery year
  1998-08-26
• Entrez gene record
  4750
• Pubmed identfication
  • 1382974
  • 8274451
• VEGA ID
  OTTHUMG00000160963

Gene info

• Identity
  HGNC:17966
• Gene
  CEP83
• Long gene name
  centrosomal protein 83
• Synonyms gene
  • CCDC41
• Synonyms gene name
  • coiled-coil domain containing 41
  • centrosomal protein 83kDa
• Synonyms
  • NY-REN-58
  • NPHP18
• GenBank acession
  • AF155115
• Locus
  12q22
• Discovery year
  2005-12-14
• Entrez gene record
  51134
• Pubmed identfication
  • 10508479
  • 23348840
• RefSeq identity
  • NM_016122
• VEGA ID
  OTTHUMG00000170242

Gene info

• Identity
  HGNC:20509
• Gene
  ZC3H14
• Long gene name
  zinc finger CCCH-type containing 14
• Synonyms
  • FLJ11806
  • UKp68
  • NY-REN-37
• GenBank acession
  • AF155107
• Locus
  14q31.3
• Discovery year
  2006-05-15
• Entrez gene record
  79882
• Pubmed identfication
  • 10508479
• RefSeq identity
  • NM_024824
• Classification
  • Zinc fingers CCCH-type
• VEGA ID
  OTTHUMG00000170803

Gene info

• Identity
  HGNC:17024
• Gene
  PHF11
• Long gene name
  PHD finger protein 11
• Synonyms
  • NY-REN-34
  • BCAP
  • IGER
• Synonyms name
  • IgE responsiveness (atopic)
• GenBank acession
  • AB011031
• Locus
  13q14.2
• Discovery year
  2003-05-08
• Entrez gene record
  51131
• Pubmed identfication
  • 10508479
  • 15057823
• RefSeq identity
  • NM_016119
• Classification
  • PHD finger proteins
• VEGA ID
  OTTHUMG00000016916

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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