Conjugated Primary Antibodies
Rabbit (Oryctolagus cuniculus)
This is a highly specific antibody against CYP8A1/PTGIS.
1ug per 1ul
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CYP8A1/PTGIS
Gene ID Number
Cross-reactive species details
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
Background of the antigen
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to prostacyclin (prostaglandin I2), a potent vasodilator and inhibitor of platelet aggregation. An imbalance of prostacyclin and its physiological antagonist thromboxane A2 contribute to the development of myocardial infarction, stroke, and atherosclerosis.
Purified by Protein A.
Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
CYP8; CYP8A1; Cytochrome P450, family 8, subfamily A, polypeptide 1; PGIS; Prostacyclin synthase; Prostaglandin I2 prostacyclin synthase; Prostaglandin I2 synthase; PTGI.
Immunoglobulin G (IgG)
Alternative to gene target
prostaglandin I2 (prostacyclin) synthase, CYP8 and CYP8A1 and PGIS and PTGI, PTGIS and IDBG-80513 and ENSG00000124212 and 5740, oxidoreductase activity, nuclei, Ptgis and IDBG-213024 and ENSMUSG00000017969 and 19223, PTGIS and IDBG-643178 and ENSBTAG00000017537 and 101910090,282021