anti-TGFbeta1 Antibody [4F9C10]
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Catalog number
32-224
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Price
Please ask
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Size
0.1 mg
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Gene info
TGF beta(transforming growth factor beta), with 390-amino acid protein (about 43 kDa), is a multifunctional peptide that controls proliferation, differentiation, and other functions in many cell types. In mammals, three isoforms of TGFbeta, that is, beta1, beta2,and beta3,are known. TGF beta is one of numerous inhibitory factors produced by cancer cells that regulate antitumor immunity. TGF beta1 takes part in the local response in the course of primary lung cancer and TGFbeta1 is thought to be implicated in breast cancer progression.TGFbeta1 also plays a critical role in the downregulation of microglial responses minimizing brain inflammation and thus avoiding exacerbation of brain damage.
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Gene names
TGFBTGF-beta-1, CED, LAP, DPD1, TGFB, TGFbeta
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Antibodie s label
unlabelled serum
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Ab raised in
Mouse
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Type
Monoclonal
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Monoclonal
4F9C10
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Immunoglobulin
IgG2a
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Antigen
Ni-NTA purified truncated recombinant TGFbeta1 expressed in E. Coli strain BL21 (DE3).
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Immuno application
ELISA, Western Blot
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Antibody advice
Western Blot:1:500 - 1:2,000 ELISA:Propose dilution 1:10,000.Determining optimal working dilutions by titration test.
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Suspention pH azide
Ascitic fluid containing 0.03% sodium azide.
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Keep at
TGF beta1 monoclonal antibody can be stored at -20 grades C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Works with
Human
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Omim nr
135674
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Ncbi nr
P01137
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NCBI GENE nr
7040
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GENE symbol
TGFB1
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Antigene name
transforming growth factor, beta 1
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Source
Homo sapiens
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Protein nr
P01137
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Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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Properties
If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translation
anticorps
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Gene target
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Short name
anti-TGFbeta1 Antibody [4F9C10]
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Technique
Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
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Alternative name
Antibody toTGFbeta1 (antibody to-) [4F9C10]
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Alternative technique
antibodies
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MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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