anti-TGFbeta1 Antibody [4F9C10]

  • Catalog number
    32-224
  • Price
    Please ask
  • Size
    0.1 mg
  • Gene info
    TGF beta(transforming growth factor beta), with 390-amino acid protein (about 43 kDa), is a multifunctional peptide that controls proliferation, differentiation, and other functions in many cell types. In mammals, three isoforms of TGFbeta, that is, beta1, beta2,and beta3,are known. TGF beta is one of numerous inhibitory factors produced by cancer cells that regulate antitumor immunity. TGF beta1 takes part in the local response in the course of primary lung cancer and TGFbeta1 is thought to be implicated in breast cancer progression.TGFbeta1 also plays a critical role in the downregulation of microglial responses minimizing brain inflammation and thus avoiding exacerbation of brain damage.
  • Gene names
    TGFBTGF-beta-1, CED, LAP, DPD1, TGFB, TGFbeta
  • Antibodie s label
    unlabelled serum
  • Ab raised in
    Mouse
  • Type
    Monoclonal
  • Monoclonal
    4F9C10
  • Immunoglobulin
    IgG2a
  • Antigen
    Ni-NTA purified truncated recombinant TGFbeta1 expressed in E. Coli strain BL21 (DE3).
  • Immuno application
    ELISA, Western Blot
  • Antibody advice
    Western Blot:1:500 - 1:2,000 ELISA:Propose dilution 1:10,000.Determining optimal working dilutions by titration test.
  • Suspention pH azide
    Ascitic fluid containing 0.03% sodium azide.
  • Keep at
    TGF beta1 monoclonal antibody can be stored at -20 grades C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Works with
    Human
  • Omim nr
    135674
  • Ncbi nr
    P01137
  • NCBI GENE nr
    7040
  • GENE symbol
    TGFB1
  • Antigene name
    transforming growth factor, beta 1
  • Source
    Homo sapiens
  • Protein nr
    P01137
  • Description
    This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
  • Properties
    If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • French translation
    anticorps
  • Gene target
  • Short name
    anti-TGFbeta1 Antibody [4F9C10]
  • Technique
    Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
  • Alternative name
    Antibody toTGFbeta1 (antibody to-) [4F9C10]
  • Alternative technique
    antibodies
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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