TLR3 Polyclonal Antibody

• Catalog number
  3445-100
• Price
  Please ask
• Size
  100 µg

• Antibody Target
  TLR3
• Target Alternative Name
  Toll Like Receptor 3
• Antibody Type
  Polyclonal
• Species Reactivities
  Human
• Immunogen Sequence
  Recombinant human TLR3
• Accession
  O15455
• Gene Id
  7098
• Appearance
  Colorless liquid
• Form
  Liquid
• Concentration
  0.5 mg/ml
• Formulation
  100 µl antigen affinity purified rabbit anti-human TLR3 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol and 0.02% thimerosal.
• Purification
  Affinity purified rabbit IgG
• Application
  Western blot
• Application And Usages
  Western blot: 1-4 µg
• Description
  To date, at least ten members of the Toll family have been identified. TLRs recognize molecular patterns associated with microbial pathogens and induce antimicrobial immune response. TLR3 recognizes double-stranded (ds)RNA, induces the activation of NF-kB, through MyD88-dependent and –independent pathways, and the production of type I interferons (IFNs). Similar to several other members of the TLR family, TLR3 has been reported to be expressed at a very low level on the surface of human fibroblast cell lines.
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans.
• Handling
  The antibody solution should be gently mixed before use.
• Western Blot Verified
  Verified
• Immunocytochemistry Verified
  Not Verified
• Immunofluorescence Verified
  Not Verified
• Immunoprecipitation Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Dot Blot Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Group
  Polyclonals and antibodies
• About
  Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
• French translation
  anticorps

• Gene target
  TLR3  
• Gene symbol
  TLR3
• Short name
  TLR3 Polyclonal Antibody
• Technique
  Polyclonal, Antibody, antibodies against human proteins, antibodies for, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
• Isotype
  Rabbit IgG
• Alternative name
  toll-like receptor 3 polyclonal (antibody to-)
• Alternative technique
  polyclonals, antibodies
• Alternative to gene target
  toll-like receptor 3, CD283 and IIAE2, TLR3 and IDBG-47294 and ENSG00000164342 and 7098, protein binding, Cell surfaces, Tlr3 and IDBG-152685 and ENSMUSG00000031639 and 142980, TLR3 and IDBG-628571 and ENSBTAG00000008682 and 281535

Gene info

• Identity
  HGNC:11849
• Gene
  TLR3
• Long gene name
  toll like receptor 3
• Synonyms gene name
  • toll-like receptor 3
• Synonyms
  • CD283
• GenBank acession
  • U88879
• Locus
  4q35.1
• Discovery year
  1998-06-25
• Entrez gene record
  7098
• Pubmed identfication
  • 9435236
• Classification
  • Toll like receptors
  • CD molecules
• VEGA ID
  OTTHUMG00000160345
• Locus Specific Databases
  • TLR3base: Mutation registry for Influenza-associated encephalopathy
  • LRG_117

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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