Rabbit Anti Human,Rat IL10RB Antibody-Non-conjugated
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Catalog numberCSB-PA600091LA01HU_50ug
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PricePlease ask
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Size50ug
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Long nameRabbit Antibody against Human, Rat IL10RB, Non-conjugated
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Synonym nameIL10RB Human, Rat Antibody
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Species reactivityHuman,Rat
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Tested applications recommended dilutionsELISA,WB,IHC;Recommended dilution:WB:1:500-1:5000,IHC:1:500-1:1000
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ConjugationNon-conjugated
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Antibody isotypeIgG
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UniProt IDQ08334
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FormatLiquid, diluted in buffer
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Buffer compositionPreservative: 0.03% Proclin 300, Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
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Purity>95%
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Purification methodProtein G purified
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Antibody categoryPolyclonal Antibodies
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Immunogen typeRecombinant Human Interleukin-10 receptor subunit beta protein (79-219AA)
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Immunogen speciesHuman
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AliasInterleukin-10 receptor subunit beta,IL-10 receptor subunit beta,IL-10R subunit beta,IL-10RB,Cytokine receptor class-II member 4,Cytokine receptor family 2 member 4,CRF2-4,Interleukin-10 receptor subunit 2,IL-10R subunit 2,IL-10R2,,CDw210b,IL10RB,CRFB4,D21S58,D21S66
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BackgroundShared cell surface receptor required for the activation of five class 2 cytokines: IL10, IL22, IL26, IL28, and IFNL1. The IFNLR1/IL10RB dimer is a receptor for the cytokine ligands IFNL2 and IFNL3 and mediates their antiviral activity. The ligand/receptor complex stimulate the activation of the JAK/STAT signaling pathway leading to the expression of IFN-stimulated genes (ISG), which contribute to the antiviral state.
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ClonalityPolyclonal antibody
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Shipping and storageIL10RB Antibody is shipped on ice packs and upon receipt should be stored at -20 or -80 degrees Celsius. We recommend that you prepare the working aliquots in advance so that freez-thaw cycles are avoided. Do not expose the antibodies to drirect bright light, especially the labeled ones as most conjugates are light sensitive.
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Short name of the antigenInterleukin-10 receptor subunit beta
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody against the Hu protein or peptide or recombinant supplied in 1 volumes. Ask for quote if you need bulk.
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PropertiesIf you buy Antibodies supplied by Cusabio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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AboutRabbits are used for polyclonal antibody production by Cusabio. Rabbit antibodies are very stable and can be stored for several days at room temperature. Cusabio adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long. Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.
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Latin nameOryctolagus cuniculus, Rattus norvegicus
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French translationanticorps
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Gene target
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Gene symbolIL10RB-DT, IL10RB
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Short nameAnti-IL10RB
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Techniqueanti human, Antibody, Rabbit, anti, antibody to, anti human antibodies, antibodies against human proteins, antibodies for, antibody Conjugates
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HostRabbit, Rabbits
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SpeciesRat, Humans, Rats
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Alternative nameIL10RB Antibody
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Alternative techniqueantibodies, rabbit-anti
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Alternative to gene targetinterleukin 10 receptor, beta, CDW210B and CRF2-4 and CRFB4 and D21S58 and D21S66 and IL-10R2, IL10RB and IDBG-401888 and ENSG00000243646 and 3588, protein binding, Plasma membranes
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Gene info
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Identity
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Gene
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Long gene nameIL10RB divergent transcript
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Synonyms gene
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Synonyms gene name
- IL10RB antisense RNA 1 (head to head)
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Synonyms
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Synonyms name
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Locus
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Discovery year2013-05-17
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Entrez gene record
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RefSeq identity
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Classification
- Divergent transcripts
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameinterleukin 10 receptor subunit beta
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Synonyms gene
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Synonyms gene name
- interleukin 10 receptor, beta
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Synonyms
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GenBank acession
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Locus
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Discovery year1993-04-06
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Entrez gene record
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Pubmed identfication
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Classification
- Interleukin receptors
- CD molecules
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data