BMS-345541 (Free base)
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Catalog numberB1907-5
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PricePlease ask
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Size5 mg
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Alternative_nameN-(1,8-Dimethylimidazo[1,2-a]quinoxalin-4-yl)-1,2-ethanediamine
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DescriptionBMS-345541 is a highly selective inhibitor of IKK-1 and IKK-2 with IC₅₀ value of 4 μM and 0.3 μM, respectively. It binds at an allosteric site of the enzyme and blocks NF-kappa B-dependent transcription in mice. Cell-permeable.
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CAS Number445430-58-0
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Structure AvailableYes
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Salt FormNo
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Molecular FormulaC₁₄H₁₇N₅
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Molecular Weight255.32
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Cell PermeableYes
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Purity≥98% by HPLC
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SolubilitiesDMSO (~ 5 mg/ml)
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HandlingProtect from air and light
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Tag LineA highly selective inhibitor of IKK-1 and IKK-2
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Storage Condition-20°C
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Shipping Conditiongel pack
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Shelf Life36 months
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MDL NumberMFCD07784499
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PubChem CID9813758
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SMILESCC1=CC2=C(C=C1)N=C(C3=NC=C(N23)C)NCCN
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InChiInChI=1S/C14H17N5/c1-9-3-4-11-12(7-9)19-10(2)8-17-14(19)13(18-11)16-6-5-15/h3-4,7-8H,5-6,15H2,1-2H3,(H,16,18)
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InChi KeyPSPFQEBFYXJZEV-UHFFFAOYSA-N
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MSDS AvailableYes
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Gene target
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Short nameBMS-345541 (Free base)
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Alternative nameBMS-345541 (Free base)
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