BMS-345541 (Free base)

  • Catalog number
    B1907-5
  • Price
    Please ask
  • Size
    5 mg
  • Alternative_name
    N-(1,8-Dimethylimidazo[1,2-a]quinoxalin-4-yl)-1,2-ethanediamine
  • Description
    BMS-345541 is a highly selective inhibitor of IKK-1 and IKK-2 with IC₅₀ value of 4 μM and 0.3 μM, respectively. It binds at an allosteric site of the enzyme and blocks NF-kappa B-dependent transcription in mice. Cell-permeable.
  • CAS Number
    445430-58-0
  • Structure Available
    Yes
  • Salt Form
    No
  • Molecular Formula
    C₁₄H₁₇N₅
  • Molecular Weight
    255.32
  • Cell Permeable
    Yes
  • Purity
    ≥98% by HPLC
  • Solubilities
    DMSO (~ 5 mg/ml)
  • Handling
    Protect from air and light
  • Tag Line
    A highly selective inhibitor of IKK-1 and IKK-2
  • Storage Condition
    -20°C
  • Shipping Condition
    gel pack
  • Shelf Life
    36 months
  • MDL Number
    MFCD07784499
  • PubChem CID
    9813758
  • SMILES
    CC1=CC2=C(C=C1)N=C(C3=NC=C(N23)C)NCCN
  • InChi
    InChI=1S/C14H17N5/c1-9-3-4-11-12(7-9)19-10(2)8-17-14(19)13(18-11)16-6-5-15/h3-4,7-8H,5-6,15H2,1-2H3,(H,16,18)
  • InChi Key
    PSPFQEBFYXJZEV-UHFFFAOYSA-N
  • MSDS Available
    Yes
  • Gene target
    BMS-345541   Free   base  
  • Short name
    BMS-345541 (Free base)
  • Alternative name
    BMS-345541 (Free base)
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