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Antigene
LSD1
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Conjugation
unconjugated
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General description
This is a high quality and purity LSD1 pAb from Rabbit.
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Application
Our LSD1 pAb from Rabbit is designed to be used in different types of immunoassays (Western blot, Immunohistochemistry etc.).
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Storage
Unless specifically stated otherwise in the product data sheet, the LSD1 Polyclonal Antibody, Rabbit, 100UL should be stored upon delivery at a temperature range between 2 and 8 degrees Celsius and at -20 degrees Celsius for longer periods of time.
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Gene
Lysine-specific demethylase 1 (LSD1), the first identified histone demethylase, was belonged to the superfamily of the Flavin adenine dinucleotide (FAD)-dependent amine oxidases. LSD1 specifically demethylates mono- or dimethylated dimethylated histone H3 lysine4 (H3K4) and H3 lysine 9 (H3K9) via a redox process. Recently evidences showed that LSD1 played an important role in a broad spectrum of biological processes, including cell proliferation, adipogenesis, spermatogenesis, chromosome segregation and embryonic development. Furthermore, LSD1 also could promote progress of tumor by inhibiting the tumor suppressor activity of p53. To date, as a potential drug for discovering anti-tumor drugs, the medical significance of LSD1 inhibitors have been greatly appreciated. Here, we reviewed the remarkable progress being made in understanding of LSD1, mainly on its structure, basic function and medical application in tumor therapy.
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About
Rabbits are used for polyclonal antibody production by Arbor Assays. Rabbit antibodies are very stable and can be stored for several days at room temperature. Arbor Assays adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
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Latin name
Oryctolagus cuniculus
