anti-KSHVORF45 Antibody [2D4A5]

• Catalog number
  32-228
• Price
  Please ask
• Size
  0.1 mL

• Gene info
  Kaposi's sarcoma-associated herpesvirus (KSHV) belongs to the gamma-(2)-herpesvirus subfamily and has been closely linked to the Kaposi’s sarcoma, primary effusion lymphoma (PEL) and multicentric Castleman’s disease. The genome of KSHV is 165-170 kb and contains at least 88 open reading frames. ORF45 protein encoded by an immediate-early gene in the KSHV genome is characterized as a phosphorylated protein, and it is localized in the cytoplasm of infected cells. Studies have shown that ORF45 Protein interacted with cellular IRF-7 and blocked virus-mediated phosphorylation and nuclear translocation of IRF-7. In consequence, ORF45 efficiently inhibited virus-induced production of type I IFN. Zhu et al (2003) reported that the ORF45 Protein was associated with purified virions.
• Gene names
  Protein ORF45
• Antibodie s label
  unlabelled serum
• Ab raised in
  Mouse
• Type
  Monoclonal
• Monoclonal
  2D4A5
• Immunoglobulin
  IgG1
• Antigen
  Ni-NTA purified recombinant human KSHV ORF45 expressed in E. Coli strain BL21 (DE3).
• Immuno application
  ELISA, Western Blot
• Antibody advice
  Western Blot:1:500 - 1,000ELISA:Determining optimal working dilutions by titration test.
• Suspention pH azide
  Ascitic fluid containing 0.03% sodium azide.
• Keep at
  to KSHV ORF45 monoclonal antibody can be stored at -20 grades C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
• Works with
  Virus
• Omim nr
  550540839
• Ncbi nr
  F5HDE4
• NCBI GENE nr
  4961474
• GENE symbol
  ORF45
• Antigene name
  virion phosphoprotein
• Source
  Human herpesvirus 8
• Protein nr
  F5HDE4
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  KSHVORF45   [2D4A5]  
• Short name
  anti-KSHVORF45 Antibody [2D4A5]
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toKSHVORF45 (antibody to-) [2D4A5]
• Alternative technique
  antibodies

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Similar products