BMF

• Catalog number
  3334R-30T
• Price
  Please ask
• Size
  30 µg

• Antibody Target
  BMF
• Target Alternative Name
  BMF, FLJ00065, Bcl-2-modifying factor
• Antibody Type
  Polyclonal
• Species Reactivities
  Human, mouse, rat
• Immunogen Sequence
  Synthetic peptide surrounding amino acid 9 of human BMF
• Accession
  Q96LC9
• Gene Id
  90427
• Appearance
  Colorless liquid
• Form
  Liquid
• Concentration
  0.5 mg/ml
• Formulation
  30 µg (0.5 mg/ml) affinity purified rabbit anti-BMF polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.
• Purification
  Affinity purified
• Application
  Western blot, Immunohistochemistry
• Positive Control
  Western Blot: Jurkat cell lysate and Rat kidney tissue lysate. IHC: Kidney tissue
• Application And Usages
  Western blotting (0.5-4 µg/ml) and Immunohistochemistry (5 µg/ml). However, the optimal conditions should be determined individually. The antibody recognizes ~28 kDa BMF in sample from human, mouse and rat origins. Reactivity to other species has not been tested.
• Description
  Bmf (for Bcl-2-modifying factor) is a novel BH3-only protein recently identified in human and mouse. The BH3 domain in Bmf is required for both binding to Bcl-2 proteins and for triggering apoptosis. In healthy cells, Bmf associates with the dynein light chain 2 (DLC2) component of the myosin V motors and is sequestered by the cell's actin cytoskeleton. Disruption of the actin cytoskeleton, either by depolymerization of actin filaments or by detachment of cells from the extracellular matrix, triggers release and activation of Bmf, initiating the downstream apoptosis program.
• Storage Condition
  -20 °C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans.
• Handling
  The antibody solution should be gently mixed before use.
• Western Blot Verified
  Verified
• Immunocytochemistry Verified
  Verified
• Immunofluorescence Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link

• Gene target
  BMF  
• Gene symbol
  BMF, BMF-AS1
• Short name
  BMF
• Isotype
  Rabbit IgG
• Alternative name
  Bcl2 modifying factor
• Alternative to gene target
  Bcl2 modifying factor, BMF and IDBG-6070 and ENSG00000104081 and 90427, protein binding, Plasma membranes, Bmf and IDBG-198160 and ENSMUSG00000040093 and 171543, BMF and IDBG-646206 and ENSBTAG00000012180 and 541141

Gene info

• Identity
  HGNC:24132
• Gene
  BMF
• Long gene name
  Bcl2 modifying factor
• Synonyms
  • FLJ00065
• GenBank acession
  • BC060783
• Locus
  15q15.1
• Discovery year
  2004-01-16
• Entrez gene record
  90427
• Pubmed identfication
  • 11546872
• RefSeq identity
  • NM_033503
• Classification
  • BCL2 homology region 3 (BH3) only
• VEGA ID
  OTTHUMG00000129875

Gene info

• Identity
  HGNC:53612
• Gene
  BMF-AS1
• Long gene name
  BMF antisense RNA 1
• Locus
  15q15.1
• Discovery year
  2017-07-06
• Classification
  • Antisense RNAs

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