Alpha 2 Antiplasmin, Human Plasma

• Catalog number
  7295-100
• Price
  Please ask
• Size
  100 ug

• Synonyms
  Alpha-2-plasmin inhibitor, SERPINF2, AAP, PLI
• Alternative_names
  Alpha-2-plasmin inhibitor, SERPINF2, AAP, PLI
• Description
  Physiological inhibitor of the serine protease plasmin.
• Recombinant
  No
• Source
  Human Plasma
• Purity by SDS PAGE
  ≥95%
• Assay
  SDS-PAGE
• Molecular Weight
  70 kDa
• Storage Temp
  -20°C
• Shipping
  Gel Pack
• Shelf Life
  12 months
• Appearance
  Lyophilized
• Physical form description
  Lyophilized from 20 mM Bis-Tris, pH 6.4, with 200 mM NaCl.
• Reconstitution Instructions
  In water or aqueous buffer
• Background Information
  Alpha 2 Antiplasmin is a member of the Serpin superfamily and the primary physiological inhibitor of the serine protease plasmin, which is responsible for the dissolution of fibrin clots. In addition to plasmin, it is also an efficient inhibitor of trypsin and chymotrypsin. Liver and kidney are major sites of its production and other tissues such as muscle, intestine, central nervous system, and placenta also express its mRNA at a moderate level. The tissue expression pattern indicates that it is a key regulator of plasmin mediated proteolysis in these tissues. Alpha-Antiplasmin-deficiency is a rare coagulation disorder which allows unrestrained fibrinolytic activity. Individuals with this condition may receive therapeutic A2AP prior to surgery to prevent postoperative hemorrhaging.
• Handling
  Centrifuge the vial prior to opening.
• Usage
  For Research Use Only! Not to be used in humans
• Datasheet
• Additional description
  The Alpha 2 Antiplasmin, Plasma is a α- or alpha protein sometimes glycoprotein present in blood.
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.

• Gene target
  Alpha   Antiplasmin   Plasma  
• Short name
  Alpha 2 Antiplasmin, Plasma
• Species
  Human, Humans
• Alternative name
  a 2 Antiplasmin, H. sapiens Plasma

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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